Literature DB >> 19811937

Low back pain may be caused by disturbed pain regulation: a cross-sectional study in low back pain patients using tender point examination.

Ole Kudsk Jensen1, Claus Vinther Nielsen, Kristian Stengaard-Pedersen.   

Abstract

BACKGROUND: Widespread pain has negative influence on outcome in low back pain (LBP) patients. Tender point (TP) examination is a standardized examination method to estimate diffuse tenderness. AIMS: To assess diffuse tenderness by means of a standardized TP examination and to analyse for associations between the number of TPs and spinal structural changes as well as psycho-social factors.
METHODS: Patients sick-listed 3-16 weeks due to LBP with or without sciatica completed a questionnaire and went through a clinical low back examination and TP examination. Of 326 patients 111 had verified nerve root affection and 215 had non-specific LBP with or without radiating pain. Disc height reductions were estimated on lateral X-rays.
RESULTS: Multivariate logistic regression analysis showed that more than 8 TPs were strongly negatively associated with disc degeneration (Odds Ratio (OR) 0.58 (0.40-84), 95% Confidence Interval (CI): 0.39-0.84, p=0.004) and verified nerve root affection (OR 0.15 (0.04-0.54), p=0.004) and were positively associated with number of years since first episode of LBP (OR 1.05, CI: 1.01-1.09, p=0.009). Furthermore, more than 8 TPs were positively associated with widespread pain, female sex and bodily distress. With all patients included, bodily distress and the number of tender points were positively associated with the intensity of LBP, but disc degeneration was only positively associated with LBP in patients with less than 6 TPs.
CONCLUSIONS: The pain in patients with diffuse tenderness was rarely related to disc degeneration or nerve root affection, rather it may be caused by disturbed pain regulation. Copyright 2009 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved.

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Year:  2009        PMID: 19811937     DOI: 10.1016/j.ejpain.2009.09.002

Source DB:  PubMed          Journal:  Eur J Pain        ISSN: 1090-3801            Impact factor:   3.931


  10 in total

1.  Low pressure pain thresholds are associated with, but does not predispose for, low back pain.

Authors:  Søren O'Neill; Per Kjær; Thomas Graven-Nielsen; Claus Manniche; Lars Arendt-Nielsen
Journal:  Eur Spine J       Date:  2011-04-22       Impact factor: 3.134

2.  Central sensitization and changes in conditioned pain modulation in people with chronic nonspecific low back pain: a case-control study.

Authors:  Juliana Barbosa Corrêa; Leonardo Oliveira Pena Costa; Naiane Teixeira Bastos de Oliveira; Kathleen A Sluka; Richard Eloin Liebano
Journal:  Exp Brain Res       Date:  2015-05-12       Impact factor: 1.972

3.  Reply to Jensen, O.K. On the Use of Quantitative Sensory Testing to Estimate Central Sensitization in Humans. Comment on "Schuttert et al. The Definition, Assessment, and Prevalence of (Human Assumed) Central Sensitisation in Patients with Chronic Low Back Pain: A Systematic Review. J. Clin. Med. 2021, 10, 5931".

Authors:  Ingrid Schuttert; Hans Timmerman; Kristian K Petersen; Megan E McPhee; Lars Arendt-Nielsen; Michiel F Reneman; André P Wolff
Journal:  J Clin Med       Date:  2022-04-11       Impact factor: 4.964

4.  Relationship between temporomandibular disorders, widespread palpation tenderness, and multiple pain conditions: a case-control study.

Authors:  Hong Chen; Gary Slade; Pei Feng Lim; Vanessa Miller; William Maixner; Luda Diatchenko
Journal:  J Pain       Date:  2012-10       Impact factor: 5.820

5.  The relationship between catastrophizing and altered pain sensitivity in patients with chronic low-back pain.

Authors:  Samantha M Meints; Ishtiaq Mawla; Vitaly Napadow; Jian Kong; Jessica Gerber; Suk-Tak Chan; Ajay D Wasan; Ted J Kaptchuk; Christina McDonnell; Junie Carriere; Bruce Rosen; Randy L Gollub; Robert R Edwards
Journal:  Pain       Date:  2019-04       Impact factor: 7.926

6.  On the Use of Quantitative Sensory Testing to Estimate Central Sensitization in Humans. Comment on Schuttert et al. The Definition, Assessment, and Prevalence of (Human Assumed) Central Sensitisation in Patients with Chronic Low Back Pain: A Systematic Review. J. Clin. Med. 2021, 10, 5931.

Authors:  Ole Kudsk Jensen
Journal:  J Clin Med       Date:  2022-04-02       Impact factor: 4.241

7.  Reproducibility of tender point examination in chronic low back pain patients as measured by intrarater and inter-rater reliability and agreement: a validation study.

Authors:  Ole Kudsk Jensen; Jacob Callesen; Merete Graakjaer Nielsen; Torkell Ellingsen
Journal:  BMJ Open       Date:  2013-02-26       Impact factor: 2.692

8.  Back pain was less explained than leg pain: a cross-sectional study using magnetic resonance imaging in low back pain patients with and without radiculopathy.

Authors:  Ole Kudsk Jensen; Claus Vinther Nielsen; Joan Solgaard Sørensen; Kristian Stengaard-Pedersen
Journal:  BMC Musculoskelet Disord       Date:  2015-12-03       Impact factor: 2.362

9.  The relationship between psychological distress and multiple tender points across the adult lifespan.

Authors:  Deborah Brown; Matthew Mulvey; Lis Cordingley; Amir Rashid; Michael Horan; Neil Pendleton; Rosie Duncan; John McBeth
Journal:  Arch Gerontol Geriatr       Date:  2015-11-07       Impact factor: 3.250

10.  Diffuse central sensitization in low back patients: A secondary analysis of cross-sectional data including tender point examination and magnetic resonance imaging of the lumbar spine.

Authors:  Ole Kudsk Jensen; Claus Vinther Nielsen; Kristian Stengaard-Pedersen
Journal:  Medicine (Baltimore)       Date:  2020-09-18       Impact factor: 1.817

  10 in total

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