Literature DB >> 19810719

A photocontrolled molecular switch regulates paralysis in a living organism.

Usama Al-Atar1, Rylan Fernandes, Bob Johnsen, David Baillie, Neil R Branda.   

Abstract

Using light to modulate biochemical agents in living organisms has a significant impact on photodynamic therapy and drug release. We demonstrate that a photoresponsive system can reversibly induce paralysis in nematodes as a model for living organisms when two different wavelengths of light are used to toggle the molecular switch between its two structural forms. This example illustrates how photoswitches offer great potential for advancing biomedical technologies.

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Year:  2009        PMID: 19810719     DOI: 10.1021/ja903070u

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  6 in total

1.  Molecular photoswitches: the worm that turned off.

Authors:  Neil Withers
Journal:  Nat Chem       Date:  2010-01       Impact factor: 24.427

Review 2.  Molecular photoswitches in aqueous environments.

Authors:  Jana Volarić; Wiktor Szymanski; Nadja A Simeth; Ben L Feringa
Journal:  Chem Soc Rev       Date:  2021-11-15       Impact factor: 54.564

3.  Dyotropic rearrangement of bridgehead substituents in closed dithienylethenes; conjugated verses non-conjugated analogues.

Authors:  Tariq Mahmood; Muhammad Arshad; Mazhar Amjad Gilani; Zafar Iqbal; Khurshid Ayub
Journal:  J Mol Model       Date:  2015-12-03       Impact factor: 1.810

4.  Azobenzene Modified Imidacloprid Derivatives as Photoswitchable Insecticides: Steering Molecular Activity in a Controllable Manner.

Authors:  Zhiping Xu; Lina Shi; Danping Jiang; Jiagao Cheng; Xusheng Shao; Zhong Li
Journal:  Sci Rep       Date:  2015-10-05       Impact factor: 4.379

5.  Photochromic coenzyme Q derivatives: switching redox potentials with light.

Authors:  Nadja A Simeth; Andrea C Kneuttinger; Reinhard Sterner; Burkhard König
Journal:  Chem Sci       Date:  2017-07-20       Impact factor: 9.825

6.  Computational and Crystallographic Examination of Naphthoquinone Based Diarylethene Photochromes.

Authors:  Dinesh G Patel; Martial Boggio-Pasqua; Travis B Mitchell; Ian M Walton; William R Quigley; Frank A Novak
Journal:  Molecules       Date:  2020-06-05       Impact factor: 4.411

  6 in total

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