Literature DB >> 1980995

Assignment of the polymorphic intestinal mucin gene (MUC2) to chromosome 11p15.

B Griffiths1, D J Matthews, L West, J Attwood, S Povey, D M Swallow, J R Gum, Y S Kim.   

Abstract

A cDNA coding for a mucin expressed in intestine has recently been cloned (Gum et al. 1989). We describe here the use of this cDNA to map the gene (MUC2) to human chromosome 11 using somatic cell hybrids, and to make the regional localization to 11p15 by in situ hybridization. Analysis of the CEPH (Centre d'Etude du Polymorphisme Humain) families revealed that MUC2 forms part of the tight linkage group on 11p15 which contains HRAS, INS, TH and HBBC.

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Year:  1990        PMID: 1980995     DOI: 10.1111/j.1469-1809.1990.tb00383.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  11 in total

1.  Size polymorphisms due to changes in the number of O-glycosylated tandem repeats in the Dictyostelium discoideum glycoprotein PsA.

Authors:  A A Gooley; R Marshchalek; K L Williams
Journal:  Genetics       Date:  1992-04       Impact factor: 4.562

2.  MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism.

Authors:  N W Toribara; J R Gum; P J Culhane; R E Lagace; J W Hicks; G M Petersen; Y S Kim
Journal:  J Clin Invest       Date:  1991-09       Impact factor: 14.808

3.  Chromosomal mapping of three mucin genes in the rat.

Authors:  K Klinga-Levan; J R Gum; S J Gendler; Y Kim; G C Hansson
Journal:  Mamm Genome       Date:  1996-03       Impact factor: 2.957

4.  Genomic organization of the 3'-region of the human MUC5AC mucin gene: additional evidence for a common ancestral gene for the 11p15.5 mucin gene family.

Authors:  M P Buisine; J L Desseyn; N Porchet; P Degand; A Laine; J P Aubert
Journal:  Biochem J       Date:  1998-06-15       Impact factor: 3.857

5.  MUC1 expressed in PanC1 cells decreases adhesion to type 1 collagen but increases contraction in collagen lattices.

Authors:  M J Hudson; G W Stamp; M A Hollingsworth; M Pignatelli; E N Lalani
Journal:  Am J Pathol       Date:  1996-03       Impact factor: 4.307

6.  Characterization of the regulatory 5'-flanking region of bovine mucin 2 (MUC2) gene.

Authors:  Melissa Shizue de Almeida Yamashita; Luna Nascimento Vargas; Eduardo de Oliveira Melo
Journal:  Mol Cell Biochem       Date:  2021-03-17       Impact factor: 3.396

7.  Mucin-bacterial interactions in the human oral cavity and digestive tract.

Authors:  Muriel Derrien; Mark Wj van Passel; Jeroen Hb van de Bovenkamp; Raymond G Schipper; Willem M de Vos; Jan Dekker
Journal:  Gut Microbes       Date:  2010-06-23

8.  Locus heterogeneity of autosomal dominant long QT syndrome.

Authors:  M Curran; D Atkinson; K Timothy; G M Vincent; A J Moss; M Leppert; M Keating
Journal:  J Clin Invest       Date:  1993-08       Impact factor: 14.808

9.  Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?

Authors:  V Guyonnet Duperat; J P Audie; V Debailleul; A Laine; M P Buisine; S Galiegue-Zouitina; P Pigny; P Degand; J P Aubert; N Porchet
Journal:  Biochem J       Date:  1995-01-01       Impact factor: 3.857

10.  Suggestive evidence for two different mucin genes in rat intestine.

Authors:  I A Khatri; G G Forstner; J F Forstner
Journal:  Biochem J       Date:  1993-09-01       Impact factor: 3.857

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