Literature DB >> 19809554

A case of neutrophilia related to a cytokine-producing relapsed squamous cell carcinoma of the uterine cervix arising from the rectovaginal septum.

Geon Park1, Young Jin Park, Yo Sup Lim, Tae Gyu Ahn, Sei Jun Han.   

Abstract

Paraneoplastic neutrophilia caused by a squamous cell carcinoma of the uterine cervix has been seen rarely. We report a case of relapsed squamous cell carcinoma of the uterine cervix with severe neutrophilia, rapid tumor growth and aggressive clinical course, possibly due to autocrine stimulation of cell growth by G-CSF and IL-6 without other possible causes of neutrophilia.

Entities:  

Keywords:  G-CSF; IL-6; Paraneoplastic syndrome; Squamous cell carcinoma; Uterine cervix

Year:  2009        PMID： 19809554      PMCID： PMC2757565          DOI： 10.3802/jgo.2009.20.3.187

Source DB:  PubMed          Journal:  J Gynecol Oncol        ISSN： 2005-0380            Impact factor:   4.401


  9 in total

Review 1.  Lineage-specific hematopoietic growth factors.

Authors:  Kenneth Kaushansky
Journal:  N Engl J Med       Date:  2006-05-11       Impact factor: 91.245

2.  A case of uterine cervical cancer presenting with granulocytosis.

Authors:  Heui June Ahn; Yeon Hee Park; Yoon Hwan Chang; Sun Hoo Park; Min-Suk Kim; Baek Yeol Ryoo; Sung Hyun Yang
Journal:  Korean J Intern Med       Date:  2005-09       Impact factor: 2.884

3.  Granulocytosis associated with tumor cell production of colony-stimulating activity.

Authors:  W Hocking; J Goodman; D Golde
Journal:  Blood       Date:  1983-03       Impact factor: 22.113

4.  A case of cervical cancer with aggressive tumor growth: possible autocrine growth stimulation by G-CSF and Il-6.

Authors:  S Kyo; T Kanaya; M Takakura; M Inoue
Journal:  Gynecol Oncol       Date:  2000-09       Impact factor: 5.482

Review 5.  Concomitant hydroxyurea plus radiotherapy versus radiotherapy for carcinoma of the uterine cervix: a systematic review.

Authors:  R P Symonds; M Collingwood; J Kirwan; C E Humber; J F Tierney; J A Green; C Williams
Journal:  Cancer Treat Rev       Date:  2004-08       Impact factor: 12.111

6.  The acute phase protein response in patients receiving subcutaneous IL-6.

Authors:  R E Banks; M A Forbes; M Storr; J Higginson; D Thompson; J Raynes; J M Illingworth; T J Perren; P J Selby; J T Whicher
Journal:  Clin Exp Immunol       Date:  1995-10       Impact factor: 4.330

7.  Extreme leucocytosis: not always leukaemia.

Authors:  C J M Halkes; H M Dijstelbloem; S J Eelkman Rooda; M H H Kramer
Journal:  Neth J Med       Date:  2007 Jul-Aug       Impact factor: 1.422

Review 8.  Paraneoplastic syndromes.

Authors:  S S Agarwala
Journal:  Med Clin North Am       Date:  1996-01       Impact factor: 5.456

Review 9.  Paraneoplastic syndromes in patients with primary head and neck cancer.

Authors:  Alfio Ferlito; Mohamed N Elsheikh; Johannes J Manni; Alessandra Rinaldo
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-01-06       Impact factor: 3.236
  9 in total

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