Literature DB >> 19808048

Fc receptors: role in biology and antibody therapy.

Jan G J van de Winkel1.   

Abstract

Insight into the biological role of antibody (Fc) receptors on immune and endothelial cells increased profoundly over the last decades. Fc receptors have been found to be crucial for normal immunity and to play an important role in the mechanisms of action of antibody therapeutics. This knowledge is key in designing and optimizing novel therapeutic strategies for human disease.

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Year:  2009        PMID： 19808048     DOI： 10.1016/j.imlet.2009.09.005

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  4 in total

1.  Crystal structure of Fcγ receptor I and its implication in high affinity γ-immunoglobulin binding.

Authors:  Jinghua Lu; Jeff L Ellsworth; Nels Hamacher; Si Won Oak; Peter D Sun
Journal:  J Biol Chem       Date:  2011-09-29       Impact factor: 5.157

Review 2.  The role of Fc receptors in HIV prevention and therapy.

Authors:  Austin W Boesch; Eric P Brown; Margaret E Ackerman
Journal:  Immunol Rev       Date:  2015-11       Impact factor: 12.988

3.  The novel immunotoxin HM1.24-ETA' induces apoptosis in multiple myeloma cells.

Authors:  M Staudinger; P Glorius; R Burger; C Kellner; K Klausz; A Günther; R Repp; W Klapper; M Gramatzki; M Peipp
Journal:  Blood Cancer J       Date:  2014-06-13       Impact factor: 9.812

4.  A novel Fc-engineered human ICAM-1/CD54 antibody with potent anti-myeloma activity developed by cellular panning of phage display libraries.

Authors:  Katja Klausz; Michael Cieker; Christian Kellner; Hans-Heinrich Oberg; Dieter Kabelitz; Thomas Valerius; Renate Burger; Martin Gramatzki; Matthias Peipp
Journal:  Oncotarget       Date:  2017-09-05
  4 in total

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