| Literature DB >> 19808016 |
Ivana De Domenico1, Jerry Kaplan.
Abstract
The unfolded protein response (UPR) coordinates translational and transcriptional changes triggered by unfolded proteins within the endoplasmic reticulum. Two recent papers (Oliveira et al., 2009; Vecchi et al., 2009) show that the UPR modulates transcription of the hormone hepcidin, which controls plasma iron levels and perhaps innate immunity.Entities:
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Year: 2009 PMID： 19808016 DOI： 10.1016/j.cmet.2009.09.005
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287