Literature DB >> 1980756

The structure of the homeodomain and its functional implications.

W J Gehring1, M Müller, M Affolter, A Percival-Smith, M Billeter, Y Q Qian, G Otting, K Wüthrich.   

Abstract

The three-dimensional structure of the homeodomain, as determined by nuclear magnetic resonance spectroscopy, reveals the presence of a helix-turn-helix motif, similar to the one found in prokaryotic gene regulatory proteins. Isolated homeodomains bind with high affinity to specific DNA sequences. Thus, the structure-function relationship is highly conserved in evolution.

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Year:  1990        PMID： 1980756     DOI： 10.1016/0168-9525(90)90253-3

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  61 in total

1.  Characterization of the KNOX class homeobox genes Oskn2 and Oskn3 identified in a collection of cDNA libraries covering the early stages of rice embryogenesis.

Authors:  A D Postma-Haarsma; I I Verwoert; O P Stronk; J Koster; G E Lamers; J H Hoge; A H Meijer
Journal:  Plant Mol Biol       Date:  1999-01       Impact factor: 4.076

2.  Target selectivity of bicoid is dependent on nonconsensus site recognition and protein-protein interaction.

Authors:  C Zhao; V Dave; F Yang; T Scarborough; J Ma
Journal:  Mol Cell Biol       Date:  2000-11       Impact factor: 4.272

3.  The invention of WUS-like stem cell-promoting functions in plants predates leptosporangiate ferns.

Authors:  Judith Nardmann; Wolfgang Werr
Journal:  Plant Mol Biol       Date:  2011-11-11       Impact factor: 4.076

4.  Differential DNA binding properties of three human homeodomain proteins.

Authors:  M T Corsetti; P Briata; L Sanseverino; A Daga; I Airoldi; A Simeone; G Palmisano; C Angelini; E Boncinelli; G Corte
Journal:  Nucleic Acids Res       Date:  1992-09-11       Impact factor: 16.971

5.  Hox-1.11 and Hox-4.9 homeobox genes.

Authors:  A Nazarali; Y Kim; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

Review 6.  Arabidopsis mutants reveal multiple roles for sterols in plant development.

Authors:  Steven D Clouse
Journal:  Plant Cell       Date:  2002-09       Impact factor: 11.277

7.  Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters.

Authors:  M Zannini; H Francis-Lang; D Plachov; R Di Lauro
Journal:  Mol Cell Biol       Date:  1992-09       Impact factor: 4.272

Review 8.  Hox genes and their candidate downstream targets in the developing central nervous system.

Authors:  Z N Akin; A J Nazarali
Journal:  Cell Mol Neurobiol       Date:  2005-06       Impact factor: 5.046

9.  The homeobox gene ATK1 of Arabidopsis thaliana is expressed in the shoot apex of the seedling and in flowers and inflorescence stems of mature plants.

Authors:  J Dockx; N Quaedvlieg; G Keultjes; P Kock; P Weisbeek; S Smeekens
Journal:  Plant Mol Biol       Date:  1995-07       Impact factor: 4.076

10.  Cloning of rat homeobox genes.

Authors:  Y Sakoyama; I Mizuta; N Ogasawara; H Yoshikawa
Journal:  Biochem Genet       Date:  1994-10       Impact factor: 1.890
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