Literature DB >> 1980692

The benzodiazepines as drugs of abuse.

J O Cole1, R J Chiarello.   

Abstract

Benzodiazepines are rarely used as "party" or "good time" drugs. Recent studies of drug abuse liability have found that benzodiazepines are minor euphoriants: they are neither sought nor valued on the same level as cocaine, methaqualone, or even alcohol. Although they do have mild to moderate euphoriant effects in recreational drug users, detoxified chronic alcoholics and, at very high dosages, detoxified sedative "addicts", only a small proportion of patients entering drug abuse treatment programs cite benzodiazepine use as their primary drug problem. However, it is difficult to estimate the extent to which benzodiazepines are primary drugs of abuse, i.e. the extent of their ability to induce euphoria with psychic dependence and active drug-seeking behavior. This may be due in part to inconsistent or ambiguous reporting terminology and reliance on laboratory studies without comparisons with actual street use. In addition, it is unclear if patients admitted to emergency rooms for non-medical use of benzodiazepines are typical of all patients who abuse these drugs. This article will examine the current data available on benzodiazepine abuse and will assess the extent to which benzodiazepines are used as primary drugs of abuse.

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Year:  1990        PMID: 1980692     DOI: 10.1016/0022-3956(90)90045-r

Source DB:  PubMed          Journal:  J Psychiatr Res        ISSN: 0022-3956            Impact factor:   4.791


  4 in total

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Authors:  R Shandera
Journal:  Can Fam Physician       Date:  1996-05       Impact factor: 3.275

2.  The effects of temazepam and ethanol on human psychomotor performance.

Authors:  G W Kunsman; J E Manno; M A Przekop; B R Manno; C M Kunsman
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

Review 3.  Polydrug abuse: a review of opioid and benzodiazepine combination use.

Authors:  Jermaine D Jones; Shanthi Mogali; Sandra D Comer
Journal:  Drug Alcohol Depend       Date:  2012-08-02       Impact factor: 4.492

4.  High-Dose Benzodiazepine Dependence: A Qualitative Study of Patients' Perceptions on Initiation, Reasons for Use, and Obtainment.

Authors:  Michael Liebrenz; Marcel Schneider; Anna Buadze; Marie-Therese Gehring; Anish Dube; Carlo Caflisch
Journal:  PLoS One       Date:  2015-11-10       Impact factor: 3.240

  4 in total

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