OBJECTIVES: We evaluated the effectiveness and safety of a disinfectant newly developed by our laboratories for use against influenza viruses. METHODS: The effectiveness of our new disinfectant against avian, swine and human influenza viruses was tested in ovo. The acute toxicity of this disinfectant to two different cultured cell lines was investigated. RESULTS: This new disinfectant showed very strong anti-influenza viral activity in the in ovo tests. All of the influenza viruses tested were inactivated very quickly. Following exposure to the disinfectant, the infectivity of all viral strains tested had been eliminated within ≤10 min. The infectant showed a weak acute toxicity in vitro. CONCLUSION: This new disinfectant is expected to be useful for preventing viral infection during a new influenza pandemic.
OBJECTIVES: We evaluated the effectiveness and safety of a disinfectant newly developed by our laboratories for use against influenza viruses. METHODS: The effectiveness of our new disinfectant against avian, swine and human influenza viruses was tested in ovo. The acute toxicity of this disinfectant to two different cultured cell lines was investigated. RESULTS: This new disinfectant showed very strong anti-influenza viral activity in the in ovo tests. All of the influenza viruses tested were inactivated very quickly. Following exposure to the disinfectant, the infectivity of all viral strains tested had been eliminated within ≤10 min. The infectant showed a weak acute toxicity in vitro. CONCLUSION: This new disinfectant is expected to be useful for preventing viral infection during a new influenza pandemic.
Authors: H Chen; G J D Smith; S Y Zhang; K Qin; J Wang; K S Li; R G Webster; J S M Peiris; Y Guan Journal: Nature Date: 2005-07-14 Impact factor: 49.962