Literature DB >> 19806236

Breakthrough in diabetes therapy ... Just around the corner?

William A Rudert1, Massimo Trucco.   

Abstract

Inspired by the articles presented in this issue of The Review of Diabetic Studies, we considered it useful to summarize the latest achievements and current challenges we face in the search for a cure of type 1 diabetes. In this editorial article, we took into account how the research landscape has changed in only a few years. While modern lifestyles impose new concerns, now we have a better knowledge of the various aspects of the disease that can be used to treat our young patients with more appropriate approaches, thereby eliminating old and obsolete prejudices.

Entities:  

Year:  2009        PMID: 19806236      PMCID: PMC2779011          DOI: 10.1900/RDS.2009.6.76

Source DB:  PubMed          Journal:  Rev Diabet Stud        ISSN: 1613-6071


  14 in total

1.  Decision time for pancreatic islet-cell transplantation.

Authors:  Piero Ruggenenti; Andrea Remuzzi; Giuseppe Remuzzi
Journal:  Lancet       Date:  2008-03-15       Impact factor: 79.321

2.  Five-year follow-up after clinical islet transplantation.

Authors:  Edmond A Ryan; Breay W Paty; Peter A Senior; David Bigam; Eman Alfadhli; Norman M Kneteman; Jonathan R T Lakey; A M James Shapiro
Journal:  Diabetes       Date:  2005-07       Impact factor: 9.461

3.  Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years.

Authors:  Kevan C Herold; Stephen Gitelman; Carla Greenbaum; Jennifer Puck; William Hagopian; Peter Gottlieb; Peter Sayre; Peter Bianchine; Emelita Wong; Vicki Seyfert-Margolis; Kasia Bourcier; Jeffrey A Bluestone
Journal:  Clin Immunol       Date:  2009-05-14       Impact factor: 3.969

4.  Long-term controlled normoglycemia in diabetic non-human primates after transplantation with hCD46 transgenic porcine islets.

Authors:  D J van der Windt; R Bottino; A Casu; N Campanile; C Smetanka; J He; N Murase; H Hara; S Ball; B E Loveland; D Ayares; F G Lakkis; D K C Cooper; M Trucco
Journal:  Am J Transplant       Date:  2009-10-21       Impact factor: 8.086

5.  Thymus-specific deletion of insulin induces autoimmune diabetes.

Authors:  Yong Fan; William A Rudert; Maria Grupillo; Jing He; Giorgia Sisino; Massimo Trucco
Journal:  EMBO J       Date:  2009-08-13       Impact factor: 11.598

6.  Histopathology of type 1 diabetes: old paradigms and new insights.

Authors:  Ken T Coppieters; Matthias G von Herrath
Journal:  Rev Diabet Stud       Date:  2009-08-10

7.  Allelic variation of Ets1 does not contribute to NK and NKT cell deficiencies in type 1 diabetes susceptible NOD mice.

Authors:  Margaret A Jordan; Lynn D Poulton; Julie M Fletcher; Alan G Baxter
Journal:  Rev Diabet Stud       Date:  2009-08-10

8.  Inflammation in Diabetic Encephalopathy is Prevented by C-Peptide.

Authors:  Anders A F Sima; Weixian Zhang; Christian W Kreipke; José A Rafols; William H Hoffman
Journal:  Rev Diabet Stud       Date:  2009-05-10

9.  Phenotypic type 2 diabetes in obese youth: insulin sensitivity and secretion in islet cell antibody-negative versus -positive patients.

Authors:  Hala Tfayli; Fida Bacha; Neslihan Gungor; Silva Arslanian
Journal:  Diabetes       Date:  2008-12-10       Impact factor: 9.461

10.  Recovery of endogenous beta-cell function in nonhuman primates after chemical diabetes induction and islet transplantation.

Authors:  Rita Bottino; Angela Criscimanna; Anna Casu; Jing He; Dirk J Van der Windt; William A Rudert; Carla Giordano; Massimo Trucco
Journal:  Diabetes       Date:  2008-11-10       Impact factor: 9.461

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