Literature DB >> 19806013

HIF-1alpha versus HIF-2alpha in endothelial cells and vascular functions: is there a master in angiogenesis regulation?

Nicolas Skuli, M Celeste Simon.   

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Year:  2009        PMID： 19806013      PMCID： PMC3144027          DOI： 10.4161/cc.8.20.9618

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  17 in total

1.  Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate.

Authors:  Holger Diez; Andreas Fischer; Anja Winkler; Cheng-Jun Hu; Antonis K Hatzopoulos; Georg Breier; Manfred Gessler
Journal:  Exp Cell Res       Date:  2006-09-19       Impact factor: 3.905

2.  Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.

Authors:  Irene Noguera-Troise; Christopher Daly; Nicholas J Papadopoulos; Sandra Coetzee; Pat Boland; Nicholas W Gale; Hsin Chieh Lin; George D Yancopoulos; Gavin Thurston
Journal:  Nature       Date:  2006-12-21       Impact factor: 49.962

3.  The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling.

Authors:  J Peng; L Zhang; L Drysdale; G H Fong
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-18       Impact factor: 11.205

4.  Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion.

Authors:  Jeffrey S Scehnet; Weidong Jiang; S Ram Kumar; Valery Krasnoperov; Alexandre Trindade; Rui Benedito; Dusan Djokovic; Cristina Borges; Eric J Ley; Antonio Duarte; Parkash S Gill
Journal:  Blood       Date:  2007-02-20       Impact factor: 22.113

5.  Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.

Authors:  Philip S Hodkinson; Paul A Elliott; Yatish Lad; Brian J McHugh; Alison C MacKinnon; Christopher Haslett; Tariq Sethi
Journal:  J Biol Chem       Date:  2007-07-30       Impact factor: 5.157

6.  HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

Authors:  Kelly L Covello; James Kehler; Hongwei Yu; John D Gordan; Andrew M Arsham; Cheng-Jun Hu; Patricia A Labosky; M Celeste Simon; Brian Keith
Journal:  Genes Dev       Date:  2006-03-01       Impact factor: 11.361

7.  Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis.

Authors:  Nicolas Skuli; Liping Liu; Anja Runge; Tao Wang; Lijun Yuan; Sunny Patel; Luisa Iruela-Arispe; M Celeste Simon; Brian Keith
Journal:  Blood       Date:  2009-05-13       Impact factor: 22.113

8.  Purification and characterization of hypoxia-inducible factor 1.

Authors:  G L Wang; G L Semenza
Journal:  J Biol Chem       Date:  1995-01-20       Impact factor: 5.157

Review 9.  Targeting hypoxia cell signaling for cancer therapy.

Authors:  Giovanni Melillo
Journal:  Cancer Metastasis Rev       Date:  2007-06       Impact factor: 9.264

10.  Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

Authors:  Nan Tang; Lianchun Wang; Jeffrey Esko; Frank J Giordano; Yan Huang; Hans-Peter Gerber; Napoleone Ferrara; Randall S Johnson
Journal:  Cancer Cell       Date:  2004-11       Impact factor: 31.743
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  13 in total

1.  Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis.

Authors:  Goutam Ghosh; Indira V Subramanian; Neeta Adhikari; Xiaoxiao Zhang; Hemant P Joshi; David Basi; Y S Chandrashekhar; Jennifer L Hall; Sabita Roy; Yan Zeng; Sundaram Ramakrishnan
Journal:  J Clin Invest       Date:  2010-10-25       Impact factor: 14.808

2.  Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes.

Authors:  Nicolas Skuli; Amar J Majmundar; Bryan L Krock; Rickson C Mesquita; Lijoy K Mathew; Zachary L Quinn; Anja Runge; Liping Liu; Meeri N Kim; Jiaming Liang; Steven Schenkel; Arjun G Yodh; Brian Keith; M Celeste Simon
Journal:  J Clin Invest       Date:  2012-03-19       Impact factor: 14.808

3.  Functional importance of Dicer protein in the adaptive cellular response to hypoxia.

Authors:  J J David Ho; Julie L Metcalf; Matthew S Yan; Paul J Turgeon; Jenny Jing Wang; Maria Chalsev; Tania N Petruzziello-Pellegrini; Albert K Y Tsui; Jeff Z He; Helena Dhamko; H S Jeffrey Man; G Brett Robb; Bin T Teh; Michael Ohh; Philip A Marsden
Journal:  J Biol Chem       Date:  2012-06-28       Impact factor: 5.157

4.  The role of endothelial HIF-1 αin the response to sublethal hypoxia in C57BL/6 mouse pups.

Authors:  Qi Li; Michael Michaud; Chan Park; Yan Huang; Rachael Couture; Frank Girodano; Michael L Schwartz; Joseph A Madri
Journal:  Lab Invest       Date:  2017-01-16       Impact factor: 5.662

5.  Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury.

Authors:  Pinelopi P Kapitsinou; Hideto Sano; Mark Michael; Hanako Kobayashi; Olena Davidoff; Aihua Bian; Bing Yao; Ming-Zhi Zhang; Raymond C Harris; Kevin J Duffy; Connie L Erickson-Miller; Timothy A Sutton; Volker H Haase
Journal:  J Clin Invest       Date:  2014-05-01       Impact factor: 14.808

6.  Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1-dependent apoptotic pathway.

Authors:  Hai-Xiang Sun; Yang Xu; Xin-Rong Yang; Wei-Min Wang; Haibo Bai; Ruo-Yu Shi; Suresh K Nayar; Ranjan P Devbhandari; Yi-zhou He; Qin-Feng Zhu; Yun-Fan Sun; Bo Hu; Mehtab Khan; Robert A Anders; Jia Fan
Journal:  Hepatology       Date:  2013-02-07       Impact factor: 17.425

7.  Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension.

Authors:  Beata Wojciak-Stothard; Vahitha B Abdul-Salam; Ka Hou Lao; Hilda Tsang; David C Irwin; Christina Lisk; Zoe Loomis; Kurt R Stenmark; John C Edwards; Stuart H Yuspa; Luke S Howard; Robert J Edwards; Christopher J Rhodes; J Simon R Gibbs; John Wharton; Lan Zhao; Martin R Wilkins
Journal:  Circulation       Date:  2014-02-06       Impact factor: 29.690

8.  Vulnerability of the developing brain to hypoxic-ischemic damage: contribution of the cerebral vasculature to injury and repair?

Authors:  Ana A Baburamani; C Joakim Ek; David W Walker; Margie Castillo-Melendez
Journal:  Front Physiol       Date:  2012-11-09       Impact factor: 4.566

9.  Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success.

Authors:  Cristina Branco-Price; Na Zhang; Moritz Schnelle; Colin Evans; Dörthe M Katschinski; Debbie Liao; Lesley Ellies; Randall S Johnson
Journal:  Cancer Cell       Date:  2012-01-17       Impact factor: 31.743

10.  Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma.

Authors:  Wei Xu; Wang Zhou; Mo Cheng; Jing Wang; Zhian Liu; Shaohui He; Xiangji Luo; Wending Huang; Tianrui Chen; Wangjun Yan; Jianru Xiao
Journal:  Sci Rep       Date:  2017-01-11       Impact factor: 4.379
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