Literature DB >> 1980446

Antihypertensive effect of tryptic hydrolysate of milk casein in spontaneously hypertensive rats.

H Karaki1, K Doi, S Sugano, H Uchiwa, R Sugai, U Murakami, S Takemoto.   

Abstract

1. Repeated oral administrations of tryptic hydrolysate of bovine milk casein (CEI) showed antihypertensive effect in spontaneously hypertensive rats. 2. Single oral administration of CEI antagonized the pressor response to angiotensin I. 3. Bovine milk casein hydrolysate inhibited the angiotensin I-converting enzyme (ACE) activity. Three peptides with ACE-inhibiting activity were isolated from CEI. 4. It is suggested that ACE-inhibiting peptides in the tryptic hydrolysate milk casein are absorbed from the intestinal tract and produce an antihypertensive effect.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 1980446

Source DB:  PubMed          Journal:  Comp Biochem Physiol C        ISSN： 0742-8413


  11 in total

1.  Hemopressin is an inverse agonist of CB1 cannabinoid receptors.

Authors:  Andrea S Heimann; Ivone Gomes; Camila S Dale; Rosana L Pagano; Achla Gupta; Laura L de Souza; Augusto D Luchessi; Leandro M Castro; Renata Giorgi; Vanessa Rioli; Emer S Ferro; Lakshmi A Devi
Journal:  Proc Natl Acad Sci U S A       Date:  2007-12-12       Impact factor: 11.205

2.  Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis.

Authors:  Heng Tang; Juan Zhang; Ke Shi; Hideki Aihara; Guocheng Du
Journal:  Biochem Biophys Res Commun       Date:  2019-03-23       Impact factor: 3.575

Review 3.  Clinical applications of bioactive milk components.

Authors:  David R Hill; David S Newburg
Journal:  Nutr Rev       Date:  2015-07       Impact factor: 7.110

Review 4.  Molecular targets of antihypertensive peptides: understanding the mechanisms of action based on the pathophysiology of hypertension.

Authors:  Kaustav Majumder; Jianping Wu
Journal:  Int J Mol Sci       Date:  2014-12-24       Impact factor: 5.923

5.  Milk-derived bioactive peptides inhibit human endothelial-monocyte interactions via PPAR-γ dependent regulation of NF-κB.

Authors:  Simone Marcone; Karen Haughton; Paul J Simpson; Orina Belton; Desmond J Fitzgerald
Journal:  J Inflamm (Lond)       Date:  2015-01-20       Impact factor: 4.981

6.  A novel peptide that improves metabolic parameters without adverse central nervous system effects.

Authors:  Patrícia Reckziegel; William T Festuccia; Luiz R G Britto; Karen L Lopes Jang; Carolina M Romão; Joel C Heimann; Manoela V Fogaça; Naielly S Rodrigues; Nicole R Silva; Francisco S Guimarães; Rosangela A S Eichler; Achla Gupta; Ivone Gomes; Lakshmi A Devi; Andrea S Heimann; Emer S Ferro
Journal:  Sci Rep       Date:  2017-11-01       Impact factor: 4.379

Review 7.  Peptides from Natural or Rationally Designed Sources Can Be Used in Overweight, Obesity, and Type 2 Diabetes Therapies.

Authors:  Mayara C F Gewehr; Renata Silverio; José Cesar Rosa-Neto; Fabio S Lira; Patrícia Reckziegel; Emer S Ferro
Journal:  Molecules       Date:  2020-02-29       Impact factor: 4.411

8.  Use of α-Lactalbumin and Caseinoglycomacropeptide as Biopeptide Precursors and as Functional Additives in Milk Beverages Fermented by L. helveticus.

Authors:  Katarzyna Skrzypczak; Emilia Fornal; Dorota Domagała; Waldemar Gustaw; Ewa Jabłońska-Ryś; Aneta Sławińska; Wojciech Radzki; Anna Kononiuk; Adam Waśko
Journal:  Int J Food Sci       Date:  2021-04-13

9.  Preparation and in vitro/in vivo characterization of enteric-coated nanoparticles loaded with the antihypertensive peptide VLPVPR.

Authors:  Haiyan Sun; Dong Liu; Yan Li; Xuwei Tang; Yanli Cong
Journal:  Int J Nanomedicine       Date:  2014-04-03

10.  New Intracellular Peptide Derived from Hemoglobin Alpha Chain Induces Glucose Uptake and Reduces Blood Glycemia.

Authors:  Renée N O Silva; Ricardo P Llanos; Rosangela A S Eichler; Thiago B Oliveira; Fábio C Gozzo; William T Festuccia; Emer S Ferro
Journal:  Pharmaceutics       Date:  2021-12-16       Impact factor: 6.321
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.