Literature DB >> 19801701

Possible olanzapine-induced hepatotoxicity in a young Chinese patient.

S Y Lui1, Steve Tso, M Lam, Eric F C Cheung.   

Abstract

We present a case of a 17-year-old man with first-episode schizophrenia who developed olanzapine-induced hepatitis, cholestasis, and splenomegaly, all of which were reversed after ceasing olanzapine. Clinicians prescribing olanzapine should be aware of this possible hepatotoxicity. Patient education, vigilance from clinicians, and careful clinical examination can help detect this complication early.

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Year:  2009        PMID： 19801701

Source DB:  PubMed          Journal:  Hong Kong Med J        ISSN： 1024-2708            Impact factor:   2.227


  8 in total

1.  Safety Profile of Antipsychotic Drugs: Analysis Based on a Provincial Spontaneous Reporting Systems Database.

Authors:  Kangyuan Guo; Zhanchun Feng; Shanquan Chen; Ziqi Yan; Zhiming Jiao; Da Feng
Journal:  Front Pharmacol       Date:  2022-03-09       Impact factor: 5.810

Review 2.  Hepatic Safety of Atypical Antipsychotics: Current Evidence and Future Directions.

Authors:  Mahmoud Slim; Inmaculada Medina-Caliz; Andres Gonzalez-Jimenez; M Rosario Cabello; Fermin Mayoral-Cleries; M Isabel Lucena; Raul J Andrade
Journal:  Drug Saf       Date:  2016-10       Impact factor: 5.606

3.  Olanzapine-induced hepatopathy in albino rats: A newer model for screening putative hepatoprotective agents, namely silymarin.

Authors:  Parama Sengupta; Chiranjib Bagchi; Abhishek Sharma; G Majumdar; C Dutta; Santanu Tripathi
Journal:  Indian J Pharmacol       Date:  2010-12       Impact factor: 1.200

4.  Ameliorative Effect of Curcumin on Olanzapine-induced Obesity in Sprague-Dawley Rats.

Authors:  Subramani Parasuraman; Khor Ming Zhen; Urmila Banik; Parayil Varghese Christapher
Journal:  Pharmacognosy Res       Date:  2017 Jul-Sep

Review 5.  Psychotropic drugs and liver disease: A critical review of pharmacokinetics and liver toxicity.

Authors:  Diogo Telles-Correia; António Barbosa; Helena Cortez-Pinto; Carlos Campos; Nuno B F Rocha; Sérgio Machado
Journal:  World J Gastrointest Pharmacol Ther       Date:  2017-02-06

6.  Nonalcoholic Fatty Liver Disease in Children and Adolescents Taking Atypical Antipsychotic Medications: Protocol for a Systematic Review and Meta-analysis.

Authors:  Ammar Albanna; Reem Hatem; Faisal A Nawaz; Ghadah A Al-Sharif; Mohammad Almoosa; Wid Kattan; Christos Tzivinikos; E Lila Amirali
Journal:  JMIR Res Protoc       Date:  2022-03-21

7.  Aripiprazole-induced Hepatitis: A Case Report.

Authors:  Lígia Castanheira; Elsa Fernandes; Pedro Levy; Ricardo Coentre
Journal:  Clin Psychopharmacol Neurosci       Date:  2019-11-20       Impact factor: 2.582

Review 8.  Antidepressants- and antipsychotics-induced hepatotoxicity.

Authors:  Nevena Todorović Vukotić; Jelena Đorđević; Snežana Pejić; Neda Đorđević; Snežana B Pajović
Journal:  Arch Toxicol       Date:  2021-01-05       Impact factor: 5.153
  8 in total

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