Literature DB >> 19800570

Lymphotoxins: new targets for hepatocellular carcinoma.

Augusto Villanueva1, Radoslav Savic, Josep M Llovet.   

Abstract

In this issue of Cancer Cell, Haybaeck et al. unravel the role of lymphotoxin pathway in the development of hepatocellular carcinoma (HCC). Aberrant activation of this cascade in mice livers recapitulates the stages of fibrosis and inflammation that precedes human liver cancer, providing a novel family of potential therapeutic targets.

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Year:  2009        PMID： 19800570      PMCID： PMC3677157          DOI： 10.1016/j.ccr.2009.09.012

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

Review 1.  Nuclear factor-kappaB in cancer development and progression.

Authors:  Michael Karin
Journal:  Nature       Date:  2006-05-25       Impact factor: 49.962

2.  Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma.

Authors:  Jean S Campbell; Steven D Hughes; Debra G Gilbertson; Thomas E Palmer; Matthew S Holdren; Aaron C Haran; Melissa M Odell; Renay L Bauer; Hong-Ping Ren; Harald S Haugen; Matthew M Yeh; Nelson Fausto
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-22       Impact factor: 11.205

3.  Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis.

Authors:  Eduardo Schiffer; Chantal Housset; Wulfran Cacheux; Dominique Wendum; Christèle Desbois-Mouthon; Colette Rey; François Clergue; Raoul Poupon; Véronique Barbu; Olivier Rosmorduc
Journal:  Hepatology       Date:  2005-02       Impact factor: 17.425

4.  Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment.

Authors:  Anuradha Budhu; Marshonna Forgues; Qing-Hai Ye; Hu-Liang Jia; Ping He; Krista A Zanetti; Udai S Kammula; Yidong Chen; Lun-Xiu Qin; Zhao-You Tang; Xin Wei Wang
Journal:  Cancer Cell       Date:  2006-08       Impact factor: 31.743

Review 5.  Hepatocellular carcinoma.

Authors:  Josep M Llovet; Andrew Burroughs; Jordi Bruix
Journal:  Lancet       Date:  2003-12-06       Impact factor: 79.321

6.  Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon.

Authors:  Adrian M Di Bisceglie; Mitchell L Shiffman; Gregory T Everson; Karen L Lindsay; James E Everhart; Elizabeth C Wright; William M Lee; Anna S Lok; Herbert L Bonkovsky; Timothy R Morgan; Marc G Ghany; Chihiro Morishima; Kristin K Snow; Jules L Dienstag
Journal:  N Engl J Med       Date:  2008-12-04       Impact factor: 91.245

7.  Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis.

Authors:  Kenneth K Tanabe; Antoinette Lemoine; Dianne M Finkelstein; Hiroshi Kawasaki; Tsutomu Fujii; Raymond T Chung; Gregory Y Lauwers; Yakup Kulu; Alona Muzikansky; Darshini Kuruppu; Michael Lanuti; Jonathan M Goodwin; Daniel Azoulay; Bryan C Fuchs
Journal:  JAMA       Date:  2008-01-02       Impact factor: 56.272

8.  Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

Authors:  Yujin Hoshida; Augusto Villanueva; Masahiro Kobayashi; Judit Peix; Derek Y Chiang; Amy Camargo; Supriya Gupta; Jamie Moore; Matthew J Wrobel; Jim Lerner; Michael Reich; Jennifer A Chan; Jonathan N Glickman; Kenji Ikeda; Masaji Hashimoto; Goro Watanabe; Maria G Daidone; Sasan Roayaie; Myron Schwartz; Swan Thung; Helga B Salvesen; Stacey Gabriel; Vincenzo Mazzaferro; Jordi Bruix; Scott L Friedman; Hiromitsu Kumada; Josep M Llovet; Todd R Golub
Journal:  N Engl J Med       Date:  2008-10-15       Impact factor: 91.245

9.  Sorafenib in advanced hepatocellular carcinoma.

Authors:  Josep M Llovet; Sergio Ricci; Vincenzo Mazzaferro; Philip Hilgard; Edward Gane; Jean-Frédéric Blanc; Andre Cosme de Oliveira; Armando Santoro; Jean-Luc Raoul; Alejandro Forner; Myron Schwartz; Camillo Porta; Stefan Zeuzem; Luigi Bolondi; Tim F Greten; Peter R Galle; Jean-François Seitz; Ivan Borbath; Dieter Häussinger; Tom Giannaris; Minghua Shan; Marius Moscovici; Dimitris Voliotis; Jordi Bruix
Journal:  N Engl J Med       Date:  2008-07-24       Impact factor: 91.245

10.  A lymphotoxin-driven pathway to hepatocellular carcinoma.

Authors:  Johannes Haybaeck; Nicolas Zeller; Monika Julia Wolf; Achim Weber; Ulrich Wagner; Michael Odo Kurrer; Juliane Bremer; Giandomenica Iezzi; Rolf Graf; Pierre-Alain Clavien; Robert Thimme; Hubert Blum; Sergei A Nedospasov; Kurt Zatloukal; Muhammad Ramzan; Sandra Ciesek; Thomas Pietschmann; Patrice N Marche; Michael Karin; Manfred Kopf; Jeffrey L Browning; Adriano Aguzzi; Mathias Heikenwalder
Journal:  Cancer Cell       Date:  2009-10-06       Impact factor: 31.743
  10 in total
  6 in total

1.  Significance of serum microRNA-21 in diagnosis of hepatocellular carcinoma (HCC): clinical analyses of patients and an HCC rat model.

Authors:  Xing Wang; Juan Zhang; Liang Zhou; Peng Lu; Zhi-Gang Zheng; Wei Sun; Jian-Lin Wang; Xi-Sheng Yang; Xiao-Lei Li; Ning Xia; Ning Zhang; Ke-Feng Dou
Journal:  Int J Clin Exp Pathol       Date:  2015-02-01

Review 2.  Cancer gene discovery in hepatocellular carcinoma.

Authors:  Lars Zender; Augusto Villanueva; Victoria Tovar; Daniela Sia; Derek Y Chiang; Josep M Llovet
Journal:  J Hepatol       Date:  2010-03-20       Impact factor: 25.083

Review 3.  Sorafenib: where do we go from here?

Authors:  Abby B Siegel; Sonja K Olsen; Arthur Magun; Robert S Brown
Journal:  Hepatology       Date:  2010-07       Impact factor: 17.425

4.  Positive association between lymphotoxin-alpha variation rs909253 and cancer risk: a meta-analysis based on 36 case-control studies.

Authors:  Xi Yu; Yi Huang; Changhong Li; Hailian Yang; Caide Lu; Shiwei Duan
Journal:  Tumour Biol       Date:  2013-10-18

Review 5.  Prebiotics: A Novel Approach to Treat Hepatocellular Carcinoma.

Authors:  Naz Fatima; Tasleem Akhtar; Nadeem Sheikh
Journal:  Can J Gastroenterol Hepatol       Date:  2017-05-10

6.  SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival.

Authors:  Maral Jamshidi; Rainer Fagerholm; Sofia Khan; Kristiina Aittomäki; Kamila Czene; Hatef Darabi; Jingmei Li; Irene L Andrulis; Jenny Chang-Claude; Peter Devilee; Peter A Fasching; Kyriaki Michailidou; Manjeet K Bolla; Joe Dennis; Qin Wang; Qi Guo; Valerie Rhenius; Sten Cornelissen; Anja Rudolph; Julia A Knight; Christian R Loehberg; Barbara Burwinkel; Frederik Marme; John L Hopper; Melissa C Southey; Stig E Bojesen; Henrik Flyger; Hermann Brenner; Bernd Holleczek; Sara Margolin; Arto Mannermaa; Veli-Matti Kosma; Laurien Van Dyck; Ines Nevelsteen; Fergus J Couch; Janet E Olson; Graham G Giles; Catriona McLean; Christopher A Haiman; Brian E Henderson; Robert Winqvist; Katri Pylkäs; Rob A E M Tollenaar; Montserrat García-Closas; Jonine Figueroa; Maartje J Hooning; John W M Martens; Angela Cox; Simon S Cross; Jacques Simard; Alison M Dunning; Douglas F Easton; Paul D P Pharoah; Per Hall; Carl Blomqvist; Marjanka K Schmidt; Heli Nevanlinna
Journal:  Oncotarget       Date:  2015-11-10
  6 in total

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