OBJECTIVE: Ectomesenchymal chondromyxoid tumor is a rare oral soft tissue neoplasm that should be differentiated from other neural and chondromyxoid entities. The aim of this study was to report the clinical, histological, and immunohistochemical features of 3 additional cases of this condition. METHODS: Clinical data were obtained from the clinical records and all cases were evaluated through light microscopy and immunohistochemistry to cytokeratins, vimentin, S100 protein, desmin, smooth muscle actin, and glial fibrilary acidic protein. RESULTS: All 3 cases affected the tongue as a long-lasting submucosal swelling and were managed through conservative surgery. They all showed myxoid and chondroid histological patterns, and vimentin, S100, and glial fibrilary acidic protein immunoexpression. CONCLUSIONS: These findings reinforce the typical features of ectomesenchymal chondromyxoid tumor previously described, helping to confirm and establish the clinical, histopathological, and immunohistochemical profile of this uncommon lesion.
OBJECTIVE: Ectomesenchymal chondromyxoid tumor is a rare oral soft tissue neoplasm that should be differentiated from other neural and chondromyxoid entities. The aim of this study was to report the clinical, histological, and immunohistochemical features of 3 additional cases of this condition. METHODS: Clinical data were obtained from the clinical records and all cases were evaluated through light microscopy and immunohistochemistry to cytokeratins, vimentin, S100 protein, desmin, smooth muscle actin, and glial fibrilary acidic protein. RESULTS: All 3 cases affected the tongue as a long-lasting submucosal swelling and were managed through conservative surgery. They all showed myxoid and chondroid histological patterns, and vimentin, S100, and glial fibrilary acidic protein immunoexpression. CONCLUSIONS: These findings reinforce the typical features of ectomesenchymal chondromyxoid tumor previously described, helping to confirm and establish the clinical, histopathological, and immunohistochemical profile of this uncommon lesion.
Authors: Brendan C Dickson; Cristina R Antonescu; Prokopios P Argyris; Elizabeth A Bilodeau; Martin J Bullock; Paul D Freedman; Douglas R Gnepp; Richard C Jordan; Ioannis G Koutlas; Cheng-Han Lee; Iona Leong; Mihai Merzianu; Bibianna M Purgina; Lester D R Thompson; Bret Wehrli; John M Wright; David Swanson; Lei Zhang; Justin A Bishop Journal: Am J Surg Pathol Date: 2018-10 Impact factor: 6.394
Authors: Gregório Wrublevski Pereira; Volnei David Pereira; José Antonio de Castro Pereira Junior; Rosemeri Maurici da Silva Journal: BMJ Case Rep Date: 2012-12-06
Authors: Min Gyoung Pak; Kyung Bin Kim; Nari Shin; Woo Kyung Kim; Dong Hoon Shin; Kyung Un Choi; Mee Young Sol Journal: Korean J Pathol Date: 2012-04-25