Literature DB >> 197997

Evidence for the presynaptic location of adenylate cyclase and the cyclic AMP-stimulated protein kinase which is bound to synaptic membranes.

M Weller.   

Abstract

By comparison of activities measured with either intact or ruptured synaptosomes it was found that half of the cerebral adenylate cyclase is presynaptic while all the membranes bound, cyclic AMP-stimulated protein kinase activity appears to be presynaptic with the cyclic AMP receptor facing inward.

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Substances：

Year:  1977        PMID： 197997     DOI： 10.1016/0005-2736(77)90171-7

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Stimulation of presynaptic beta-adrenoceptors enhances [3H]-noradrenaline release druing nerve stimulation in the perfused cat spleen.

Authors:  S M Celuch; M L Dubocovich; S Z Lander
Journal:  Br J Pharmacol       Date:  1978-05       Impact factor: 8.739

2.  Effect of cyclic nucleotides on [3H]-neurotransmitter release induced by potassium stimulation in the rat pineal gland [proceedings].

Authors:  M L Dubocovich; S Z Langer; F Pelayo
Journal:  Br J Pharmacol       Date:  1978-03       Impact factor: 8.739

3.  Localization of endogenous ATPases at the nerve terminal.

Authors:  R G Sorensen; H R Mahler
Journal:  J Bioenerg Biomembr       Date:  1982-12       Impact factor: 2.945

4.  Electron microscopic demonstration of adenylate cyclase activity in rat cortical synaptosomes.

Authors:  M A Rostomian; K S Abramian; F Hajós
Journal:  Histochemistry       Date:  1981

5.  The time course of the phosphorylation of proteins in the synaptic plasma membrane and the effect of certain cations.

Authors:  M Weller
Journal:  Mol Cell Biochem       Date:  1979-10-15       Impact factor: 3.396

6.  Electrokinetic properties of synaptic vesicles and synaptosomal membranes.

Authors:  D P Siegel; B R Ware
Journal:  Biophys J       Date:  1980-04       Impact factor: 4.033

7.  Cyclic AMP independent protein kinase activity in rat cerebral cortex synaptic vesicles--partial characterization.

Authors:  J Glaser; M G Weller; A C Neethling; J J Taljaard
Journal:  Neurochem Res       Date:  1982-10       Impact factor: 3.996

8.  The role of cyclic nucleotides and calcium in the mediation of the modulatory effects of octopamine on locust skeletal muscle.

Authors:  P D Evans
Journal:  J Physiol       Date:  1984-03       Impact factor: 5.182
  8 in total

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