Literature DB >> 19798495

US findings of melamine-related renal disorders in Hong Kong children.

Hang Yee Lau1, Chun Sing Wong, Johnny Ka Fai Ma, Elaine Kan, Kwong Lok Siu.   

Abstract

BACKGROUND: The melamine-tainted milk incident has caused renal disorders in more than 290,000 children from mainland China since the start of the outbreak in 2008. Since then, more than 27,000 children in Hong Kong have undergone renal US screening.
OBJECTIVE: To present and discuss the US features of melamine-related renal abnormalities in Hong Kong children.
MATERIALS AND METHODS: Between September 2008 and February 2009, 3,835 children attended the Department of Radiology of Princess Margaret Hospital for renal US examination. CT or plain abdominal radiography was performed in those with inconclusive findings. The US findings of detected melamine-related renal disorders were analysed.
RESULTS: Echogenic foci in the kidneys were found in 22 children (0.6%). These were located in the renal pelvicalyceal system (in 12 children) and in the renal medulla (in 10 children). The echogenic foci measured 0.1-0.7 cm, with 6 children showing posterior acoustic shadowing, 14 showing comet-tail artefacts, and 2 showing echogenic dots.
CONCLUSION: The incidence of renal disorders amongst Hong Kong children exposed to melamine was lower than in their mainland China counterparts. The renal stones detected were also relatively small, with most demonstrating comet-tail artefacts instead of posterior acoustic shadowing.

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Year:  2009        PMID: 19798495     DOI: 10.1007/s00247-009-1342-2

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  13 in total

1.  Sonographic mimics of renal calculi.

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2.  Estimation of ultrasound beam width in the elevation (section thickness) plane.

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Journal:  Radiology       Date:  1991-07       Impact factor: 11.105

3.  Ultrasonographic evaluation of melamine-exposed children in Hong Kong.

Authors:  Stella Sin Yee Ho; Winnie Chiu Wing Chu; Ka Tak Wong; Chi Kong Li; William Wong; Pak Cheung Ng; Anil T Ahuja
Journal:  N Engl J Med       Date:  2009-02-04       Impact factor: 91.245

4.  Clinical significance of the comet-tail artifact in thyroid ultrasound.

Authors:  A Ahuja; W Chick; W King; C Metreweli
Journal:  J Clin Ultrasound       Date:  1996 Mar-Apr       Impact factor: 0.910

5.  Diagnosis and spectrum of melamine-related renal disease: plausible mechanism of stone formation in humans.

Authors:  Ching-Wan Lam; Lawrence Lan; Xiaoyan Che; Sidney Tam; Samson Sai-Yin Wong; Yue Chen; Jing Jin; Shao-Hua Tao; Xiao-Ming Tang; Kwok-Yung Yuen; Paul Kwong-Hang Tam
Journal:  Clin Chim Acta       Date:  2009-01-09       Impact factor: 3.786

6.  Outbreaks of renal failure associated with melamine and cyanuric acid in dogs and cats in 2004 and 2007.

Authors:  Cathy A Brown; Kyu-Shik Jeong; Robert H Poppenga; Birgit Puschner; Doris M Miller; Angela E Ellis; Kyung-Il Kang; Steffen Sum; Alexis M Cistola; Scott A Brown
Journal:  J Vet Diagn Invest       Date:  2007-09       Impact factor: 1.279

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Journal:  AJR Am J Roentgenol       Date:  1991-11       Impact factor: 3.959

8.  Identification and characterization of toxicity of contaminants in pet food leading to an outbreak of renal toxicity in cats and dogs.

Authors:  Roy L M Dobson; Safa Motlagh; Mike Quijano; R Thomas Cambron; Timothy R Baker; Aletha M Pullen; Brian T Regg; Adrienne S Bigalow-Kern; Thomas Vennard; Andrew Fix; Renate Reimschuessel; Gary Overmann; Yuching Shan; George P Daston
Journal:  Toxicol Sci       Date:  2008-08-09       Impact factor: 4.849

9.  Renal stone shadowing: an investigation of contributing factors.

Authors:  W King; C Kimme-Smith; J Winter
Journal:  Radiology       Date:  1985-01       Impact factor: 11.105

10.  Melamine-contaminated powdered formula and urolithiasis in young children.

Authors:  Na Guan; Qingfeng Fan; Jie Ding; Yiming Zhao; Jingqiao Lu; Yi Ai; Guobin Xu; Sainan Zhu; Chen Yao; Lina Jiang; Jing Miao; Han Zhang; Dan Zhao; Xiaoyu Liu; Yong Yao
Journal:  N Engl J Med       Date:  2009-02-04       Impact factor: 91.245

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  3 in total

Review 1.  Melamine-related kidney stones and renal toxicity.

Authors:  Rishikesh P Dalal; David S Goldfarb
Journal:  Nat Rev Nephrol       Date:  2011-03-22       Impact factor: 28.314

2.  Melamine-induced urinary calculi in infants--sonographic manifestations and outcomes 1 year after exposure.

Authors:  Fang Nie; Xin-jie Li; Pan-feng Shang; Ying Wang
Journal:  Pediatr Radiol       Date:  2012-12-19

3.  Hong Kong Chinese school children with elevated urine melamine levels: a prospective follow up study.

Authors:  Alice P S Kong; Kai-Chow Choi; Chung Shun Ho; Michael H M Chan; Chun Kwok Wong; Eric K H Liu; Winnie C W Chu; Viola C Y Chow; Joseph T F Lau; Juliana C N Chan
Journal:  BMC Public Health       Date:  2011-05-20       Impact factor: 3.295

  3 in total

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