Literature DB >> 19797574

Vascularized iliac bone-grafting for osteonecrosis with segmental collapse of the femoral head.

Chun-Chieh Chen1, Chun-Li Lin, Wei-Chih Chen, Hsin-Nung Shih, Steve W N Ueng, Mel S Lee.   

Abstract

BACKGROUND: Vascularized iliac bone-grafting has been reported to be successful for patients with osteonecrosis of the femoral head. However, its benefit in patients with segmental collapse of the femoral head has not been determined. The purpose of this study was to analyze the results of vascularized iliac grafting in osteonecrotic femoral heads with segmental collapse.
METHODS: We retrospectively analyzed thirty-three hips in thirty-two patients in whom an osteonecrotic femoral head with segmental collapse (Association Research Circulation Osseous [ARCO] stage IIIA [<2-mm collapse] or stage IIIB [2 to 4-mm collapse]) had been treated with vascularized iliac bone-grafting between 1994 and 1999. The average age of the patients at the time of surgery was thirty-seven years. Twenty-six patients (twenty-seven hips) overused alcohol, five patients (five hips) had no known risk factor, and one patient (one hip) used corticosteroids for refractory bronchial asthma. Clinical outcomes were evaluated with the Harris hip score. We defined clinical failure as conversion to total hip replacement for any reason and radiographic failure as progressive femoral head collapse or secondary osteoarthritis of the involved hip.
RESULTS: At the conclusion of the study, only eight (24%) of the thirty-three hips were preserved. The mean survival time for the series as a whole was seventy-four months (95% confidence interval, fifty-four to ninety-five months) after the surgery. Eighteen of the twenty-six ARCO stage-IIIA hips were converted to a total hip replacement, and the mean survival time for the stage-IIIA hips was eighty-five months (95% confidence interval, sixty-one to 108 months). All of the seven ARCO stage-IIIB hips were converted to a total hip replacement, and the mean survival time for the stage-IIIB hips was thirty-five months (95% confidence interval, eleven to fifty-eight months). The mean Harris hip score for the eight hips that still survived at the time of follow-up had improved from 62 points to 80 points. However, all of them had progressive collapse of the femoral head-i.e., radiographic failure-at the time of final follow-up.
CONCLUSIONS: Vascularized iliac bone-grafting with use of the technique described in this study is not indicated for the treatment of osteonecrotic femoral heads with segmental collapse.

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Year:  2009        PMID: 19797574     DOI: 10.2106/JBJS.H.01814

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  24 in total

1.  MicroRNA-mediated interacting circuits predict hypoxia and inhibited osteogenesis of stem cells, and dysregulated angiogenesis are involved in osteonecrosis of the femoral head.

Authors:  Gour-Shenq Kao; Yuan-Kun Tu; Pei-Hsun Sung; Feng-Sheng Wang; Yu-Der Lu; Chen-Ta Wu; Rio L C Lin; Hon-Kan Yip; Mel S Lee
Journal:  Int Orthop       Date:  2018-04-26       Impact factor: 3.075

2.  Treatment of osteonecrosis of the femoral head with vascularized bone grafting.

Authors:  Patrick D Millikan; Vasili Karas; Samuel S Wellman
Journal:  Curr Rev Musculoskelet Med       Date:  2015-09

3.  Repairing defect and preventing collapse of femoral head in a steroid-induced osteonecrotic of femoral head animal model using strontium-doped calcium polyphosphate combined BM-MNCs.

Authors:  Pengde Kang; Xiaowei Xie; Zhen Tan; Jing Yang; Bin Shen; Zongke Zhou; Fuxing Pei
Journal:  J Mater Sci Mater Med       Date:  2015-01-30       Impact factor: 3.896

4.  Combination treatment of biomechanical support and targeted intra-arterial infusion of peripheral blood stem cells mobilized by granulocyte-colony stimulating factor for the osteonecrosis of the femoral head: a randomized controlled clinical trial.

Authors:  Qiang Mao; Weidong Wang; Taotao Xu; Shanxing Zhang; Luwei Xiao; Di Chen; Hongting Jin; Peijian Tong
Journal:  J Bone Miner Res       Date:  2015-04       Impact factor: 6.741

5.  Utility of tricalcium phosphate and osteogenic matrix cell sheet constructs for bone defect reconstruction.

Authors:  Tomoyuki Ueha; Manabu Akahane; Takamasa Shimizu; Yoshinobu Uchihara; Yusuke Morita; Naoya Nitta; Akira Kido; Yusuke Inagaki; Kenji Kawate; Yasuhito Tanaka
Journal:  World J Stem Cells       Date:  2015-06-26       Impact factor: 5.326

Review 6.  Are we evaluating osteonecrosis adequately?

Authors:  Gwo-Chin Lee; Marvin E Steinberg
Journal:  Int Orthop       Date:  2012-09-26       Impact factor: 3.075

Review 7.  Which factors influence preservation of the osteonecrotic femoral head?

Authors:  Jay R Lieberman; Stephen M Engstrom; R Michael Meneghini; Nelson Fong SooHoo
Journal:  Clin Orthop Relat Res       Date:  2012-02       Impact factor: 4.176

8.  Alcohol intake and the risk of osteonecrosis of the femoral head in Japanese populations: a dose-response meta-analysis of case-control studies.

Authors:  Byung-Ho Yoon; Tae-Young Kim; In-Soo Shin; Hee Young Lee; Yun Jong Lee; Kyung-Hoi Koo
Journal:  Clin Rheumatol       Date:  2017-07-06       Impact factor: 2.980

9.  Prediction of the progression of femoral head collapse in ARCO stage 2-3A osteonecrosis based on the initial bone resorption lesion.

Authors:  Shan Shi; Ping Luo; Li Sun; Limin Xie; Tong Yu; Zhenchang Wang; Xuedong Yang
Journal:  Br J Radiol       Date:  2020-11-12       Impact factor: 3.039

Review 10.  Stem cell- and growth factor-based regenerative therapies for avascular necrosis of the femoral head.

Authors:  Lars Rackwitz; Lars Eden; Stephan Reppenhagen; Johannes C Reichert; Franz Jakob; Heike Walles; Oliver Pullig; Rocky S Tuan; Maximilian Rudert; Ulrich Nöth
Journal:  Stem Cell Res Ther       Date:  2012-02-22       Impact factor: 6.832

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