| Literature DB >> 19797271 |
Abstract
Integrin transmembrane receptors orchestrate signaling cascades by recruiting cytoskeletal linker proteins and enzymes to sites of cell adhesion. A proteomics-based view of such integrin-associated signaling networks is now available. Besides the usual suspects, the interactomes contain several proteins that were not previously connected to integrins. One of these, regulator of chromosome condensation-2 (RCC2), represents an unexpected molecular connection between integrins and the cell-migration machinery.Entities:
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Year: 2009 PMID: 19797271 DOI: 10.1126/scisignal.289pe58
Source DB: PubMed Journal: Sci Signal ISSN: 1945-0877 Impact factor: 8.192