Literature DB >> 19796830

Successful treatment of isolated subglottic haemangioma with propranolol alone.

Chris G Jephson1, Francesca Manunza, Samira Syed, Nikki A Mills, John Harper, Ben E J Hartley.   

Abstract

Subglottic haemangioma is a rare but potentially life threatening condition which requires intervention. Many different treatments have been described with varying degrees of success and complications. Recently, successful treatment with propranolol has been reported in 11 cases of cutaneous haemangiomas and then in two cases of subglottic haemangiomas with extensive cutaneous lesions in conjunction with other treatment modalities. We describe the successful treatment with propranolol, of a stridulous four-month-old child with a 95% obstructing subglottic haemangioma. This was achieved without the need for tracheostomy or any other surgical intervention, and with no reported side effects. We now believe the new discovery of a dramatic response to propranolol allows treatment in the acute setting and following further study may render surgical treatment of subglottic haemangioma obsolete.

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Year:  2009        PMID: 19796830     DOI: 10.1016/j.ijporl.2009.08.020

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  16 in total

1.  Treatment with propranolol for infantile hemangiomas: A case series of 106 infants.

Authors:  Shang-Bin Li; Guang-Qi Xu; Feng Gao; Ran Huo
Journal:  Exp Ther Med       Date:  2015-05-08       Impact factor: 2.447

2.  Use of propranolol in infantile haemangiomas: report of five cases and review of the literature.

Authors:  D Gidaris; M Economou; V Hatzidemetriou; N Gombakis; M Athanassiou-Metaxa
Journal:  Hippokratia       Date:  2011-01       Impact factor: 0.471

3.  Flexible Laryngoscopy in Management of Congenital Stridor.

Authors:  Prasanna Kumar Saravanam; Vinoth Manimaran
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2017-10-06

4.  Ultrasound and colour Doppler in infantile subglottic haemangioma.

Authors:  Leo Rossler; T Rothoeft; N Teig; C Koerner-Rettberg; T Deitmer; C H L Rieger; E Hamelmann
Journal:  Pediatr Radiol       Date:  2011-09-09

Review 5.  Emergent medical and surgical management of mediastinal infantile hemangioma with symptomatic spinal cord compression: case report and literature review.

Authors:  Daniel H Fulkerson; Nnenna G Agim; George Al-Shamy; Denise W Metry; Shayan A Izaddoost; Andrew Jea
Journal:  Childs Nerv Syst       Date:  2010-04-20       Impact factor: 1.475

Review 6.  Update on pediatric extracranial vascular anomalies of the head and neck.

Authors:  Katherine B Puttgen; Monica Pearl; Aylin Tekes; Sally E Mitchell
Journal:  Childs Nerv Syst       Date:  2010-08-10       Impact factor: 1.475

Review 7.  Propranolol treatment of subglottic hemangiomas: a review of the literature.

Authors:  Lei Wu; Xiling Wu; Xuefeng Xu; Zhimin Chen
Journal:  Int J Clin Exp Med       Date:  2015-11-15

Review 8.  Initiation and use of propranolol for infantile hemangioma: report of a consensus conference.

Authors:  Beth A Drolet; Peter C Frommelt; Sarah L Chamlin; Anita Haggstrom; Nancy M Bauman; Yvonne E Chiu; Robert H Chun; Maria C Garzon; Kristen E Holland; Leonardo Liberman; Susan MacLellan-Tobert; Anthony J Mancini; Denise Metry; Katherine B Puttgen; Marcia Seefeldt; Robert Sidbury; Kendra M Ward; Francine Blei; Eulalia Baselga; Laura Cassidy; David H Darrow; Shawna Joachim; Eun-Kyung M Kwon; Kari Martin; Jonathan Perkins; Dawn H Siegel; Robert J Boucek; Ilona J Frieden
Journal:  Pediatrics       Date:  2012-12-24       Impact factor: 7.124

Review 9.  The effectiveness of propranolol in treating infantile haemangiomas: a meta-analysis including 35 studies.

Authors:  Yin Lou; Wen-jia Peng; Yi Cao; Dong-sheng Cao; Juan Xie; Hong-hong Li
Journal:  Br J Clin Pharmacol       Date:  2014-07       Impact factor: 4.335

Review 10.  Propranolol is an effective treatment for airway haemangiomas: a critical analysis and meta-analysis of published interventional studies.

Authors:  P V Vlastarakos; G X Papacharalampous; M Chrysostomou; E-F Tavoulari; A Delidis; D Protopapas; T P Nikolopoulos
Journal:  Acta Otorhinolaryngol Ital       Date:  2012-08       Impact factor: 2.124

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