Literature DB >> 19796609

Oxysterols drive dopaminergic neurogenesis from stem cells.

Dengke K Ma1, Guo-li Ming, Hongjun Song.   

Abstract

Stem cell therapy for Parkinson's disease requires effective production of dopaminergic neurons. In this issue of Cell Stem Cell, Sacchetti et al. (2009) report an unexpected role of liver X receptors and their ligand, oxysterols, in regulating dopaminergic neurogenesis.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19796609      PMCID： PMC6188706          DOI： 10.1016/j.stem.2009.09.001

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  10 in total

1.  Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease.

Authors:  O Lindvall; P Brundin; H Widner; S Rehncrona; B Gustavii; R Frackowiak; K L Leenders; G Sawle; J C Rothwell; C D Marsden
Journal:  Science       Date:  1990-02-02       Impact factor: 47.728

2.  Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells.

Authors:  Jennifer R Dwyer; Navdar Sever; Marc Carlson; Stanley F Nelson; Philip A Beachy; Farhad Parhami
Journal:  J Biol Chem       Date:  2007-01-02       Impact factor: 5.157

3.  Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.

Authors:  Hyun-Jin Kim; Xiaotang Fan; Chiara Gabbi; Konstantin Yakimchuk; Paolo Parini; Margaret Warner; Jan-Ake Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-31       Impact factor: 11.205

Review 4.  LXRS and FXR: the yin and yang of cholesterol and fat metabolism.

Authors:  Nada Y Kalaany; David J Mangelsdorf
Journal:  Annu Rev Physiol       Date:  2006       Impact factor: 19.318

5.  Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.

Authors:  Paola Sacchetti; Kyle M Sousa; Anita C Hall; Isabel Liste; Knut R Steffensen; Spyridon Theofilopoulos; Clare L Parish; Carin Hazenberg; Lars Ahrlund Richter; Outti Hovatta; Jan-Ake Gustafsson; Ernest Arenas
Journal:  Cell Stem Cell       Date:  2009-10-02       Impact factor: 24.633

6.  The oxysterol receptor LXR inhibits proliferation of human breast cancer cells.

Authors:  Lise-Lotte Vedin; Sebastian A Lewandowski; Paolo Parini; Jan-Ake Gustafsson; Knut R Steffensen
Journal:  Carcinogenesis       Date:  2009-01-23       Impact factor: 4.944

Review 7.  Stem cell-based cell therapy in neurological diseases: a review.

Authors:  Seung U Kim; Jean de Vellis
Journal:  J Neurosci Res       Date:  2009-08-01       Impact factor: 4.164

8.  Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility.

Authors:  David H Volle; Kévin Mouzat; Rajesha Duggavathi; Bénazir Siddeek; Pierre Déchelotte; Benoît Sion; Georges Veyssière; Mohamed Benahmed; Jean-Marc A Lobaccaro
Journal:  Mol Endocrinol       Date:  2007-03-06

Review 9.  Stem cell biology and neurodegenerative disease.

Authors:  R D McKay
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-05-29       Impact factor: 6.237

Review 10.  Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells.

Authors:  Emily Gale; Meng Li
Journal:  Mol Brain       Date:  2008-09-30       Impact factor: 4.041
  10 in total
  5 in total

Review 1.  LXR agonists: new potential therapeutic drug for neurodegenerative diseases.

Authors:  Pei Xu; Dabing Li; Xiaotong Tang; Xiaohang Bao; Jing Huang; Yongping Tang; Yang Yang; Haiwei Xu; Xiaotang Fan
Journal:  Mol Neurobiol       Date:  2013-04-27       Impact factor: 5.590

2.  Liver X Receptor Agonist Modifies the DNA Methylation Profile of Synapse and Neurogenesis-Related Genes in the Triple Transgenic Mouse Model of Alzheimer's Disease.

Authors:  A G Sandoval-Hernández; H G Hernández; A Restrepo; J I Muñoz; G F Bayon; A F Fernández; M F Fraga; G P Cardona-Gómez; H Arboleda; Gonzalo H Arboleda
Journal:  J Mol Neurosci       Date:  2015-11-09       Impact factor: 3.444

3.  Role of Liver X Receptor in AD Pathophysiology.

Authors:  Adrián G Sandoval-Hernández; Luna Buitrago; Herman Moreno; Gloria Patricia Cardona-Gómez; Gonzalo Arboleda
Journal:  PLoS One       Date:  2015-12-31       Impact factor: 3.240

Review 4.  O-GlcNAc: Regulator of Signaling and Epigenetics Linked to X-linked Intellectual Disability.

Authors:  Daniel Konzman; Lara K Abramowitz; Agata Steenackers; Mana Mohan Mukherjee; Hyun-Jin Na; John A Hanover
Journal:  Front Genet       Date:  2020-11-23       Impact factor: 4.599

5.  Liver X receptors agonist promotes differentiation of rat bone marrow derived mesenchymal stem cells into dopaminergic neuron-like cells.

Authors:  Oumei Cheng; Xiaoyan Tian; Ying Luo; Shaoshan Mai; Yang Yang; Shengnan Kuang; Qi Chen; Jie Ma; Beibei Chen; Rong Li; Lu Yang; Huan Li; Congli Hu; Jiahua Zhang; Zhihao Chen; Yuke Li; Hui Xia; Ying Xu; Junqing Yang
Journal:  Oncotarget       Date:  2017-12-09
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.