Literature DB >> 19795178

Flexion contractures in secondary adrenal insufficiency.

Jan Berger1, Piet Herregods, Johan Verhelst, Gaëtane Stassijns, Rudi Chappel.   

Abstract

We report the case of a 55-year-old male with flexion contractures of the hips and the knees due to an isolated adrenocorticotropin (ACTH) deficiency, a rare cause of secondary adrenal insufficiency. The presenting symptoms and signs, the laboratory investigations and the treatment are described. The case description is followed by a brief overview of ACTH deficiency and its symptoms and causes. Our case is then compared with other case reports available in the literature. The aetiology of the flexion contractures in adrenal insufficiency is still unclear. The authors want to draw attention to adrenal insufficiency as the cause of unexplained flexion contractures.

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Year:  2009        PMID: 19795178     DOI: 10.1007/s10067-009-1289-6

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN: 0770-3198            Impact factor:   2.980


  9 in total

Review 1.  Flexion contractures possibly reflect the existence of hypocortisolism.

Authors:  Tetsuo Nishikawa
Journal:  Intern Med       Date:  2003-08       Impact factor: 1.271

2.  Isolated adrenocorticotropin deficiency and flexion contractures syndrome.

Authors:  Vassiliki Syriou; Anestis Moisidis; Nikolaos Tamouridis; Krystallenia I Alexandraki; Margarita Anapliotou
Journal:  Hormones (Athens)       Date:  2008 Oct-Dec       Impact factor: 2.885

3.  Muscle contractures associated with glucocorticoid deficiency.

Authors:  R L Blandford; A K Samanta; A C Burden; F D Rosenthal
Journal:  Br Med J (Clin Res Ed)       Date:  1985-07-13

4.  Flexion contractures: a forgotten symptom in Addison's disease and hypopituitarism.

Authors:  G Ebinger; R Six; M Bruyland; G Somers
Journal:  Lancet       Date:  1986-10-11       Impact factor: 79.321

5.  [Syndrome of "contracture facio-brachio-abdomino-crurale en flexion" in a case of isolated ACTH deficiency].

Authors:  S Yabuki; F Shiomi
Journal:  Rinsho Shinkeigaku       Date:  1984-07

6.  Myalgias and muscle contractures as the presenting signs of Addison's disease.

Authors:  M S Shapiro; C Trebich; L Shilo; L Shenkman
Journal:  Postgrad Med J       Date:  1988-03       Impact factor: 2.401

Review 7.  Isolated corticotrophin deficiency.

Authors:  Massimiliano Andrioli; Francesca Pecori Giraldi; Francesco Cavagnini
Journal:  Pituitary       Date:  2006       Impact factor: 4.107

8.  [Syndrome of contracture facio-brachio-abdomino-crurale en flexion in a case of isolated ACTH deficiency--biopsy findings of muscle and nerve].

Authors:  K Nakamagoe; N Ohkoshi; A Ishii; E Oguni; H Mizusawa
Journal:  Rinsho Shinkeigaku       Date:  1994-03

9.  Flexion contractures of the legs as the initial manifestation of adrenocortical insufficiency.

Authors:  Takao Odagaki; Yoshinori Noguchi; Tsuguya Fukui
Journal:  Intern Med       Date:  2003-08       Impact factor: 1.271

  9 in total
  3 in total

1.  Painful hypoadrenalism.

Authors:  Chisho Hoshino; Noriyuki Satoh; Masashi Narita; Akio Kikuchi; Minoru Inoue
Journal:  BMJ Case Rep       Date:  2011-03-25

2.  Treatable Bedridden Elderly -Recovery from Flexion Contracture after Cortisol Replacement in a Patient with Isolated Adrenocorticotropic Hormone Deficiency.

Authors:  Takamasa Tanaka; Norihiko Terada; Yoshiki Fujikawa; Takushi Fujimoto
Journal:  Intern Med       Date:  2016-10-15       Impact factor: 1.271

3.  Adrenal Insufficiency Secondary to Abrupt Dose Reduction of Topical Corticosteroid Therapy after Starting Brodalumab for Psoriasis: A Case Report.

Authors:  Mariko Yamane; Hiroaki Hayashi; Yumi Aoyama
Journal:  Case Rep Dermatol       Date:  2022-03-31
  3 in total

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