Literature DB >> 19794479

Drug discovery: Propping up a destructive regime.

Randall T Peterson.   

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Year:  2009        PMID: 19794479     DOI: 10.1038/461599a

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  8 in total

Review 1.  Rethinking WNT signaling.

Authors:  Nicholas S Tolwinski; Eric Wieschaus
Journal:  Trends Genet       Date:  2004-04       Impact factor: 11.639

Review 2.  Mining the Wnt pathway for cancer therapeutics.

Authors:  Nick Barker; Hans Clevers
Journal:  Nat Rev Drug Discov       Date:  2006-12       Impact factor: 84.694

Review 3.  Tankyrase function at telomeres, spindle poles, and beyond.

Authors:  Susan J Hsiao; Susan Smith
Journal:  Biochimie       Date:  2007-07-24       Impact factor: 4.079

4.  APC mutations occur early during colorectal tumorigenesis.

Authors:  S M Powell; N Zilz; Y Beazer-Barclay; T M Bryan; S R Hamilton; S N Thibodeau; B Vogelstein; K W Kinzler
Journal:  Nature       Date:  1992-09-17       Impact factor: 49.962

5.  Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

Authors:  Shih-Min A Huang; Yuji M Mishina; Shanming Liu; Atwood Cheung; Frank Stegmeier; Gregory A Michaud; Olga Charlat; Elizabeth Wiellette; Yue Zhang; Stephanie Wiessner; Marc Hild; Xiaoying Shi; Christopher J Wilson; Craig Mickanin; Vic Myer; Aleem Fazal; Ronald Tomlinson; Fabrizio Serluca; Wenlin Shao; Hong Cheng; Michael Shultz; Christina Rau; Markus Schirle; Judith Schlegl; Sonja Ghidelli; Stephen Fawell; Chris Lu; Daniel Curtis; Marc W Kirschner; Christoph Lengauer; Peter M Finan; John A Tallarico; Tewis Bouwmeester; Jeffery A Porter; Andreas Bauer; Feng Cong
Journal:  Nature       Date:  2009-09-16       Impact factor: 49.962

Review 6.  The telomeric PARP, tankyrases, as targets for cancer therapy.

Authors:  H Seimiya
Journal:  Br J Cancer       Date:  2006-02-13       Impact factor: 7.640

7.  Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.

Authors:  Baozhi Chen; Michael E Dodge; Wei Tang; Jianming Lu; Zhiqiang Ma; Chih-Wei Fan; Shuguang Wei; Wayne Hao; Jessica Kilgore; Noelle S Williams; Michael G Roth; James F Amatruda; Chuo Chen; Lawrence Lum
Journal:  Nat Chem Biol       Date:  2009-01-04       Impact factor: 15.040

8.  Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.

Authors:  Y Jeffrey Chiang; Susan J Hsiao; Dena Yver; Samuel W Cushman; Lino Tessarollo; Susan Smith; Richard J Hodes
Journal:  PLoS One       Date:  2008-07-09       Impact factor: 3.240

  8 in total

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