Literature DB >> 19793560

Pathophysiology and management of the burn scar.

Adil Ladak1, Edward E Tredget.   

Abstract

Fibroproliferative disorders (FPDs) are common and serious disorders. Hypertrophic scar (HSc) and keloids represent the dermal equivalents of FPD and impose lower mortality but great morbidity. This article reviews current knowledge in the pathophysiology and molecular and cellular characteristics of postburn HSc. Additionally, current treatment modalities and future treatment options based on advancements in the understanding of the pathophysiology of HSc are discussed.

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Year:  2009        PMID: 19793560     DOI: 10.1016/j.cps.2009.05.014

Source DB:  PubMed          Journal:  Clin Plast Surg        ISSN: 0094-1298            Impact factor:   2.017


  11 in total

Review 1.  Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.

Authors:  Gerd G Gauglitz; Hans C Korting; Tatiana Pavicic; Thomas Ruzicka; Marc G Jeschke
Journal:  Mol Med       Date:  2010-10-05       Impact factor: 6.354

2.  MiR-3613-3p inhibits hypertrophic scar formation by down-regulating arginine and glutamate-rich 1.

Authors:  Lisha Li; Weiqiang Han; Yun Chen; Yuhua Chen
Journal:  Mol Cell Biochem       Date:  2020-11-09       Impact factor: 3.396

3.  Nanofat Injection for the Treatment of Depressed Facial Scars.

Authors:  Rong Huang; Hu Jiao; Jincai Fan; Liqiang Liu; Jia Tian; Cheng Gan; Zengjie Yang; Tiran Zhang; Yan Zeng; Zhiguo Su
Journal:  Aesthetic Plast Surg       Date:  2021-02-26       Impact factor: 2.326

4.  Systemic Delivery of Anti-Integrin αL Antibodies Reduces Early Macrophage Recruitment, Inflammation, and Scar Formation in Murine Burn Wounds.

Authors:  Xanthe L Strudwick; Damian H Adams; Natasha T Pyne; Michael S Samuel; Rachael Z Murray; Allison J Cowin
Journal:  Adv Wound Care (New Rochelle)       Date:  2020-01-28       Impact factor: 4.730

5.  The molecular mechanism of hypertrophic scar.

Authors:  Zhensen Zhu; Jie Ding; Heather A Shankowsky; Edward E Tredget
Journal:  J Cell Commun Signal       Date:  2013-03-18       Impact factor: 5.782

6.  Pediatric Contractures in Burn Injury: A Burn Model System National Database Study.

Authors:  Jeremy Goverman; Katie Mathews; Richard Goldstein; Radha Holavanahalli; Karen Kowalske; Peter Esselman; Nicole Gibran; Oscar Suman; David Herndon; Colleen M Ryan; Jeffrey C Schneider
Journal:  J Burn Care Res       Date:  2017 Jan/Feb       Impact factor: 1.819

7.  Functional genomics unique to week 20 post wounding in the deep cone/fat dome of the Duroc/Yorkshire porcine model of fibroproliferative scarring.

Authors:  Loren H Engrav; Christopher K Tuggle; Kathleen F Kerr; Kathy Q Zhu; Surawej Numhom; Oliver P Couture; Richard P Beyer; Anne M Hocking; Gretchen J Carrougher; Maria Luiza C Ramos; Matthew B Klein; Nicole S Gibran
Journal:  PLoS One       Date:  2011-04-20       Impact factor: 3.240

Review 8.  Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids.

Authors:  Ho Jun Lee; Yong Ju Jang
Journal:  Int J Mol Sci       Date:  2018-03-02       Impact factor: 5.923

9.  Epidemiology and Outcome Analysis of 470 Patients with Hand Burns: A Five-Year Retrospective Study in a Major Burn Center in Southwest China.

Authors:  Mian Liu; Haijie Zhu; Rongshuai Yan; Jiacai Yang; Rixing Zhan; Xunzhou Yu; Xiaohong Hu; Xiaorong Zhang; Gaoxing Luo; Wei Qian
Journal:  Med Sci Monit       Date:  2020-05-06

10.  Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars.

Authors:  Zichun Gu; Yirun Li; Hua Li
Journal:  JAMA Facial Plast Surg       Date:  2018-03-01       Impact factor: 4.611

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