| Literature DB >> 1979226 |
G Morgan1, H A Wilkins, J Pepin, O Jobe, D Brewster, H Whittle.
Abstract
Mother-to-child infection with HIV-2 is thought to be rare, and there have been few previous reports of transmission by this route. Reports of morbidity associated with HIV-2 infection in children are also rare. We describe eight children born to mothers who were infected with HIV-2; five developed AIDS, and three were still seropositive at 17-49 months of age. The only apparent route of HIV-2 transmission was from mother to child, except for one child who had been transfused. Three of the children with AIDS died, all having decreased CD4+ lymphocytes and mitogen responses. Further studies are needed to determine the prevalence and natural history of mother-to-child transmission of HIV-2.Entities:
Keywords: Africa; Africa South Of The Sahara; Age Factors; Bacterial And Fungal Diseases; Biology; Case Studies; Child; Child Mortality; Demographic Factors; Developing Countries; Diarrhea; Diseases; English Speaking Africa; Examinations And Diagnoses; Family And Household; Family Characteristics; Family Relationships; Gambia; Hiv Infections--transmission; Immunity; Immunity, Cellular; Infant; Infections; Malaria; Malnutrition; Mortality; Mothers; Nutrition Disorders; Parasitic Diseases; Parents; Physiology; Population; Population Characteristics; Population Dynamics; Research Methodology; Screening; Studies; Viral Diseases; Western Africa; Youth
Mesh：
Year: 1990 PMID： 1979226 DOI： 10.1097/00002030-199009000-00008
Source DB: PubMed Journal: AIDS ISSN： 0269-9370 Impact factor: 4.177