Literature DB >> 19788270

Bioactive scalaranes from the Thai sponge Hyrtios gumminae.

Chulabhorn Mahidol1, Hunsa Prawat, Suwannee Sangpetsiripan, Somsak Ruchirawat.   

Abstract

Chemical investigation of the Thai sponge Hyrtios gumminae collected from Similan Island in the Andaman Sea, Thailand, yielded four new sesterterpenoids, similan A (1), 12beta,20-dihydroxy-16beta-acetoxy-17-scalaren-19,20-olide (2), 12beta-acetoxy-20-hydroxy-17-scalaren-19,20-olide (3), and 12beta,16alpha,20-trihydroxy-17-scalaren-19,20-olide (4), together with seven known compounds. The structures of these new compounds were elucidated on the basis of their spectroscopic data and chemical transformations. Some of the isolated compounds were tested for their cytotoxic activity.

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Year:  2009        PMID： 19788270     DOI： 10.1021/np900267v

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  Cytotoxic sesterterpenoids from a sponge Hippospongia sp.

Authors:  Yu-Chia Chang; Shang-Wei Tseng; Li-Lian Liu; Yalan Chou; Yuan-Shing Ho; Mei-Chin Lu; Jui-Hsin Su
Journal:  Mar Drugs       Date:  2012-04-27       Impact factor: 6.085

2.  Antiproliferative Scalarane-Based Metabolites from the Red Sea Sponge Hyrtios erectus.

Authors:  Sameh S Elhady; Ahmed M Al-Abd; Ali M El-Halawany; Abdulrahman M Alahdal; Hashim A Hassanean; Safwat A Ahmed
Journal:  Mar Drugs       Date:  2016-07-08       Impact factor: 5.118

3.  Sterols from Thai Marine Sponge Petrosia (Strongylophora) sp. and Their Cytotoxicity.

Authors:  Phanruethai Pailee; Chulabhorn Mahidol; Somsak Ruchirawat; Vilailak Prachyawarakorn
Journal:  Mar Drugs       Date:  2017-02-23       Impact factor: 5.118

Review 4.  Bioactive Natural Products of Marine Sponges from the Genus Hyrtios.

Authors:  Nourhan Hisham Shady; Ebaa M El-Hossary; Mostafa A Fouad; Tobias A M Gulder; Mohamed Salah Kamel; Usama Ramadan Abdelmohsen
Journal:  Molecules       Date:  2017-05-11       Impact factor: 4.411

5.  Scalalactams A⁻D, Scalarane Sesterterpenes with a γ-Lactam Moiety from a Korean Spongia Sp. Marine Sponge.

Authors:  Inho Yang; Jusung Lee; Jihye Lee; Dongyup Hahn; Jungwook Chin; Dong Hwan Won; Jaeyoung Ko; Hyukjae Choi; Ahreum Hong; Sang-Jip Nam; Heonjoong Kang
Journal:  Molecules       Date:  2018-12-03       Impact factor: 4.411

6.  The Protective Effect of Polyherbal Formulation, Harak Formula, on UVA-Induced Photoaging of Human Dermal Fibroblasts and Mouse Skin via Promoting Nrf2-Regulated Antioxidant Defense.

Authors:  Jinapath Lohakul; Anyamanee Chaiprasongsuk; Saowanee Jeayeng; Malinee Saelim; Phetthinee Muanjumpon; Saowalak Thanachaiphiwat; Pinpat Tripatara; Kittipong Soontrapa; Natchagorn Lumlerdkij; Pravit Akarasereenont; Uraiwan Panich
Journal:  Front Pharmacol       Date:  2021-04-12       Impact factor: 5.810

7.  Anti-Helicobacter, Antitubercular and Cytotoxic Activities of Scalaranes from the Red Sea Sponge Hyrtios erectus.

Authors:  Abdulrahman M Alahdal; Hani Z Asfour; Safwat A Ahmed; Ahmad O Noor; Ahmed M Al-Abd; Mahmoud A Elfaky; Sameh S Elhady
Journal:  Molecules       Date:  2018-04-23       Impact factor: 4.411

8.  Cytotoxic Scalarane Sesterterpenes from the Sponge Hyrtios erectus.

Authors:  Oh-Seok Kwon; Donghwa Kim; Chang-Kwon Kim; Jeongyoon Sun; Chung J Sim; Dong-Chan Oh; Sang Koo Lee; Ki-Bong Oh; Jongheon Shin
Journal:  Mar Drugs       Date:  2020-05-13       Impact factor: 5.118

9.  Scalarane Sesterterpenoids with Antibacterial and Anti-Proliferative Activities from the Mushroom Neonothopanus nambi.

Authors:  Awat Wisetsai; Ratsami Lekphrom; Sureeporn Bua-Art; Thanapat Suebrasri; Sophon Boonlue; Sarawut Tontapha; Vittaya Amornkitbamrung; Thanaset Senawong; Florian T Schevenels
Journal:  Molecules       Date:  2021-12-17       Impact factor: 4.411
  9 in total

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