Literature DB >> 1978639

Thrombocytopenia due to aurothioglucose, sulphasalazine, and hydroxychloroquine.

M J Wijnands1, W A Allebes, A M Boerbooms, L B van de Putte, P L van Riel.   

Abstract

A 56 year old woman with rheumatoid arthritis developed relapsing thrombocytopenia during successive treatments with aurothioglucose, sulphasalazine, and hydroxychloroquine. The presence of IgM or IgG antibodies or immune complexes reactive with autologous platelets could not be shown. Relapsing thrombocytopenia may indicate a genetically determined HLA-DR3 and B8 aberrant immunological response to stimuli such as certain second line drugs.

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Year:  1990        PMID: 1978639      PMCID: PMC1004237          DOI: 10.1136/ard.49.10.798

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


  17 in total

1.  HLA types in patients with rheumatoid arthritis developing leucopenia after both gold and sulphasalazine treatment.

Authors:  H Bliddal; B Eiberg; P Helin; A Svejgaard
Journal:  Ann Rheum Dis       Date:  1989-07       Impact factor: 19.103

2.  Chrysotherapy and thrombocytopenia.

Authors:  R Madhok; T Pullar; H A Capell; F Dawood; R D Sturrock; H M Dick
Journal:  Ann Rheum Dis       Date:  1985-09       Impact factor: 19.103

3.  Selective erythroid and magakaryocytic aplasia after sulfasalazine administration.

Authors:  G E Davies; J Palek
Journal:  Arch Intern Med       Date:  1980-08

4.  Hypogammaglobulinaemia and thrombocytopenia associated with sulphasalazine therapy in rheumatoid arthritis.

Authors:  M Farr; E Tunn; P A Bacon; D H Smith
Journal:  Ann Rheum Dis       Date:  1985-10       Impact factor: 19.103

5.  Gold induced thrombocytopenia: platelet associated IgG and HLA typing in three patients.

Authors:  J D Adachi; W G Bensen; D P Singal; P J Powers
Journal:  J Rheumatol       Date:  1984-06       Impact factor: 4.666

6.  Immune thrombocytopenia due to a drug metabolite.

Authors:  E V Eisner; N T Shahidi
Journal:  N Engl J Med       Date:  1972-08-24       Impact factor: 91.245

7.  Gold-induced thrombocytopenia: detection of anti-platelet antibody.

Authors:  R D Armstrong; A Faith; G S Panayi; J R Batchelor
Journal:  Clin Rheumatol       Date:  1983-06       Impact factor: 2.980

8.  HLA antigens and toxic reactions to sodium aurothiomalate in patients with rheumatoid arthritis.

Authors:  W G Bensen; N Moore; P Tugwell; M D'Souza; D P Singal
Journal:  J Rheumatol       Date:  1984-06       Impact factor: 4.666

9.  Sulfisoxazole-induced thrombocytopenic purpura. Immunologic mechanism as cause.

Authors:  H E Hamilton; R F Sheets
Journal:  JAMA       Date:  1978-06-16       Impact factor: 56.272

10.  HLA associations in aurothioglucose- and D-penicillamine-induced haematotoxic reactions in rheumatoid arthritis.

Authors:  F Speerstra; P Reekers; L B van de Putte; J P Vandenbroucke
Journal:  Tissue Antigens       Date:  1985-07
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  1 in total

Review 1.  A risk-benefit assessment of slow-acting antirheumatic drugs in rheumatoid arthritis.

Authors:  A A Kalla; A F Tooke; E Bhettay; O L Meyers
Journal:  Drug Saf       Date:  1994-07       Impact factor: 5.606

  1 in total

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