Literature DB >> 19785608

The role of human endogenous retroviruses in melanoma.

S Singh1, S Kaye, M E Gore, M O McClure, C B Bunker.   

Abstract

Sequencing of the human genome has established that our DNA harbours many endogenous retrovirus (ERV) sequences, remnants of ancestral exogenous retroviral infections fixed in the germline DNA. In recent years, human ERVs (HERVs) have been implicated in melanomagenesis. Retrovirus-like particles and the expression of HERV mRNA and proteins have been demonstrated in melanoma tissue. In addition, antibodies to HERV proteins have been observed in patients with melanoma. In vitro and mouse models have provided fascinating insights into the potential mechanisms of HERVs in melanomagenesis. This review considers the evidence associating HERVs with melanoma.

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Year:  2009        PMID： 19785608     DOI： 10.1111/j.1365-2133.2009.09415.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  10 in total

1.  Inhibition of Borna disease virus replication by an endogenous bornavirus-like element in the ground squirrel genome.

Authors:  Kan Fujino; Masayuki Horie; Tomoyuki Honda; Dana K Merriman; Keizo Tomonaga
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-25       Impact factor: 11.205

Review 2.  Skin microbiota: microbial community structure and its potential association with health and disease.

Authors:  Mariana Rosenthal; Deborah Goldberg; Allison Aiello; Elaine Larson; Betsy Foxman
Journal:  Infect Genet Evol       Date:  2011-04-02       Impact factor: 3.342

3.  Biochemical analysis of the complex between the tetrameric export adapter protein Rec of HERV-K/HML-2 and the responsive RNA element RcRE pck30.

Authors:  Janina S Langner; Nina V Fuchs; Jan Hoffmann; Alexander Wittmann; Bernhard Brutschy; Roswitha Löwer; Beatrix Suess
Journal:  J Virol       Date:  2012-06-13       Impact factor: 5.103

Review 4.  Melanoma, Darwinian medicine and the inner world.

Authors:  B Krone; J M Grange
Journal:  J Cancer Res Clin Oncol       Date:  2010-09-18       Impact factor: 4.553

Review 5.  Structure and function of the human skin microbiome.

Authors:  Nina N Schommer; Richard L Gallo
Journal:  Trends Microbiol       Date:  2013-11-12       Impact factor: 17.079

6.  Multiple sclerosis: are protective immune mechanisms compromised by a complex infectious background?

Authors:  Bernd Krone; John M Grange
Journal:  Autoimmune Dis       Date:  2010-12-20

7.  Human endogenous retroviruses and cancer prevention: evidence and prospects.

Authors:  Luca Cegolon; Cristiano Salata; Elisabete Weiderpass; Paolo Vineis; Giorgio Palù; Giuseppe Mastrangelo
Journal:  BMC Cancer       Date:  2013-01-03       Impact factor: 4.430

Review 8.  HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease.

Authors:  Oliver Hohn; Kirsten Hanke; Norbert Bannert
Journal:  Front Oncol       Date:  2013-09-20       Impact factor: 6.244

Review 9.  Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?

Authors:  Ronan F Downey; Francis J Sullivan; Feng Wang-Johanning; Stefan Ambs; Francis J Giles; Sharon A Glynn
Journal:  Int J Cancer       Date:  2014-06-17       Impact factor: 7.396

10.  Human Endogenous Retrovirus Expression Is Associated with Head and Neck Cancer and Differential Survival.

Authors:  Allison R Kolbe; Matthew L Bendall; Alexander T Pearson; Doru Paul; Douglas F Nixon; Marcos Pérez-Losada; Keith A Crandall
Journal:  Viruses       Date:  2020-08-28       Impact factor: 5.818
  10 in total

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