Literature DB >> 19784572

Amino and nitro derivatives of 5,7-dimethoxyflavone from Kaempferia parviflora and cytotoxicity against KB cell line.

Suchana Wanich1, Chavi Yenjai.   

Abstract

Structural modification of 5,7-dimethoxyflavone isolated from Kaempferia parviflora furnished two nitro and seven amino derivatives. Among these, six new (3, 5-6, 8-10) and three known (2, 4, 7) flavonoid derivatives were synthesized. All compounds were evaluated for cytotoxicity against KB cell line using colorimetric method. Compounds 6 and 8 exhibited strong cytotoxicity with IC50 values of 6.80 and 5.84 microg/mL, respectively.

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Year:  2009        PMID: 19784572     DOI: 10.1007/s12272-009-1901-y

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN: 0253-6269            Impact factor:   4.946


  1 in total

1.  New flav-3-en-3-ol glycosides, kaempferiaosides C and D, and acetophenone glycosides, kaempferiaosides E and F, from the rhizomes of Kaempferia parviflora.

Authors:  Saowanee Chaipech; Toshio Morikawa; Kiyofumi Ninomiya; Masayuki Yoshikawa; Yutana Pongpiriyadacha; Takao Hayakawa; Osamu Muraoka
Journal:  J Nat Med       Date:  2011-11-20       Impact factor: 2.343

  1 in total

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