Literature DB >> 1978324

Analysis of expression of cholecystokinin in dopamine cells in the ventral mesencephalon of several species and in humans with schizophrenia.

M Schalling1, K Friberg, K Seroogy, P Riederer, E Bird, S N Schiffmann, P Mailleux, J J Vanderhaeghen, S Kuga, M Goldstein.   

Abstract

The ventral mesencephalons of hamster, guinea pig, cat, monkey, and several humans with and without the diagnosis of schizophrenia were analyzed with in situ hybridization and immunohistochemistry. Extensive codistribution of cholecystokinin mRNA and tyrosine hydroxylase [L-tyrosine, tetrahydropteridine: oxygen oxidoreductase (3-hydroxylating), EC 1.14.16.2] mRNA was observed in cats and monkeys as well as in all five human subjects with the diagnosis of schizophrenia and in two out of five control brains. Double labeling revealed coexistence of the two markers in cat, monkey, and human. No cholecystokinin mRNA or cholecystokinin peptide was detected in the substantia nigra/ventral tegmental area of the hamster or guinea pig, even after acute and chronic neuroleptic treatment.

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Year:  1990        PMID： 1978324      PMCID： PMC54969          DOI： 10.1073/pnas.87.21.8427

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  33 in total

1.  Fluorescent antibody methods.

Authors:  A H COONS
Journal:  Gen Cytochem Methods       Date:  1958

2.  Immunohistochemical studies on cholecystokinin (CCK)-immunoreactive neurons in the rat using sequence specific antisera and with special reference to the caudate nucleus and primary sensory neurons.

Authors:  T Hökfelt; M Herrera-Marschitz; K Seroogy; G Ju; W A Staines; V Holets; M Schalling; U Ungerstedt; C Post; J F Rehfeld
Journal:  J Chem Neuroanat       Date:  1988 Jan-Feb       Impact factor: 3.052

3.  Amphetamine psychosis: a "model" schizophrenia mediated by catecholamines.

Authors:  S H Snyder
Journal:  Am J Psychiatry       Date:  1973-01       Impact factor: 18.112

4.  Purification and characterization of tyrosine hydroxylase from a clonal pheochromocytoma cell line.

Authors:  K A Markey; H Kondo; L Shenkman; M Goldstein
Journal:  Mol Pharmacol       Date:  1980-01       Impact factor: 4.436

5.  Neuroleptic-like properties of cholecystokinin analogs: distinctive mechanisms underlying similar behavioral profiles depending on the route of administration.

Authors:  P De Witte; M Gewiss; B Roques; J J Vanderhaeghen
Journal:  Peptides       Date:  1988 Jul-Aug       Impact factor: 3.750

6.  Forebrain projections from cholecystokininlike-immunoreactive neurons in the rat midbrain.

Authors:  K B Seroogy; J H Fallon
Journal:  J Comp Neurol       Date:  1989-01-15       Impact factor: 3.215

7.  Complete coding sequence of rat tyrosine hydroxylase mRNA.

Authors:  B Grima; A Lamouroux; F Blanot; N F Biguet; J Mallet
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

8.  A subpopulation of mesencephalic dopamine neurons projecting to limbic areas contains a cholecystokinin-like peptide: evidence from immunohistochemistry combined with retrograde tracing.

Authors:  T Hökfelt; L Skirboll; J F Rehfeld; M Goldstein; K Markey; O Dann
Journal:  Neuroscience       Date:  1980       Impact factor: 3.590

9.  Isolation and structure of caerulein, an active decapeptide from the skin of Hyla caerulea.

Authors:  A Anastasi; V Erspamer; R Endean
Journal:  Experientia       Date:  1967-09-15

10.  Regional localization of the mRNA coding for the neuropeptide cholecystokinin in the rat brain studied by in situ hybridization.

Authors:  M Savasta; J M Palacios; G Mengod
Journal:  Neurosci Lett       Date:  1988-11-11       Impact factor: 3.046
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  5 in total

1.  Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity.

Authors:  Hiroshi Kawasaki; Hirofumi Suemori; Kenji Mizuseki; Kiichi Watanabe; Fumi Urano; Hiroshi Ichinose; Masatoshi Haruta; Masayo Takahashi; Kanako Yoshikawa; Shin-Ichi Nishikawa; Norio Nakatsuji; Yoshiki Sasai
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-29       Impact factor: 11.205

Review 2.  Understanding opioid reward.

Authors:  Howard L Fields; Elyssa B Margolis
Journal:  Trends Neurosci       Date:  2015-01-29       Impact factor: 13.837

3.  Inhibitory activity of the equine infectious anemia virus major 5' splice site in the absence of Rev.

Authors:  W Tan; M Schalling; C Zhao; M Luukkonen; M Nilsson; E M Fenyö; G N Pavlakis; S Schwartz
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

4.  Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis.

Authors:  D L Galson; J O Hensold; T R Bishop; M Schalling; A D D'Andrea; C Jones; P E Auron; D E Housman
Journal:  Mol Cell Biol       Date:  1993-05       Impact factor: 4.272

Review 5.  Cholecystokinin-Mediated Neuromodulation of Anxiety and Schizophrenia: A "Dimmer-Switch" Hypothesis.

Authors:  Santiago J Ballaz; Michel Bourin
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363
  5 in total

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