Literature DB >> 19782920

A prospective study of the management of non-massive pulmonary embolism in the home.

Matilde Rodríguez-Cerrillo1, Arántzazu Alvarez-Arcaya, Eddita Fernández-Díaz, Arturo Fernández-Cruz.   

Abstract

BACKGROUND: The objective of this study is to compare the characteristics, outcomes, and clinical complications of patients with pulmonary embolism (PE) who were treated at home as outpatients versus traditional hospitalization.
METHODS: Prospective study from January 2006 to June 2007. Selected patients diagnosed at the Emergency Department with stable non-massive pulmonary embolism that met standard inclusion criteria of Hospital at Home (HH) were treated at home. Patients that did not meet these criteria were admitted to Conventional Hospitalization (CH). Major and minor bleeding, re-thrombosis, clinical course, unexpected returns to hospital, and need for hospital re-admission in the following 3 months were recorded.
RESULTS: 61 patients with PE were included (30 HH and 31 CH). Mean age 66.8 and 66.7 years in HH and CH, respectively. A history of neoplasm was found to be present in 13.3% and 9.7% of HH and CH patients. In the CH group, 19.3% of patients had prior thromboembolic disease. Concomitant DVT was seen in 40% and 29% of HH and CH patient. Pulmonary embolism was bilateral in 30% and 38.7% of HH and CH patients. No major bleeding, re-thrombosis, or death occurred. The home treatment was successfully completed in 100% of the patients. Three patients in the CH group had hospital-acquired infections.
CONCLUSIONS: Patients with stable non-massive pulmonary embolism may be safely treated under conditions of home hospitalization.

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Year:  2009        PMID: 19782920     DOI: 10.1016/j.ejim.2009.04.003

Source DB:  PubMed          Journal:  Eur J Intern Med        ISSN: 0953-6205            Impact factor:   4.487


  10 in total

1.  Impact of relative contraindications to home management in emergency department patients with low-risk pulmonary embolism.

Authors:  David R Vinson; Carrieann E Drenten; Jie Huang; J Eileen Morley; Megan L Anderson; Mary E Reed; Daniel K Nishijima; Vincent Liu
Journal:  Ann Am Thorac Soc       Date:  2015-05

2.  National Trends in Home Treatment of Acute Pulmonary Embolism.

Authors:  Paul D Stein; Fadi Matta; Mary J Hughes
Journal:  Clin Appl Thromb Hemost       Date:  2016-10-26       Impact factor: 2.389

3.  Home vs hospital treatment of low-risk venous thromboembolism: a systematic review and meta-analysis.

Authors:  Rasha Khatib; Stephanie Ross; Sean Alexander Kennedy; Ivan D Florez; Thomas L Ortel; Robby Nieuwlaat; Ignacio Neumann; Daniel M Witt; Sam Schulman; Veena Manja; Rebecca Beyth; Nathan P Clark; Wojtek Wiercioch; Holger J Schünemann; Yuqing Zhang
Journal:  Blood Adv       Date:  2020-02-11

4.  Identification of patients with low-risk pulmonary embolism suitable for outpatient treatment using the pulmonary embolism severity index (PESI).

Authors:  A McCabe; T Hassan; M Doyle; B McCann
Journal:  Ir J Med Sci       Date:  2012-11-28       Impact factor: 1.568

5.  Timing of discharge follow-up for acute pulmonary embolism: retrospective cohort study.

Authors:  David R Vinson; Dustin W Ballard; Jie Huang; Adina S Rauchwerger; Mary E Reed; Dustin G Mark
Journal:  West J Emerg Med       Date:  2015-01-12

6.  Comprehensive Outpatient Management of Low-Risk Pulmonary Embolism: Can Primary Care Do This? A Narrative Review.

Authors:  David R Vinson; Drahomir Aujesky; Geert-Jan Geersing; Pierre-Marie Roy
Journal:  Perm J       Date:  2020-03-13

7.  American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism.

Authors:  Thomas L Ortel; Ignacio Neumann; Walter Ageno; Rebecca Beyth; Nathan P Clark; Adam Cuker; Barbara A Hutten; Michael R Jaff; Veena Manja; Sam Schulman; Caitlin Thurston; Suresh Vedantham; Peter Verhamme; Daniel M Witt; Ivan D Florez; Ariel Izcovich; Robby Nieuwlaat; Stephanie Ross; Holger J Schünemann; Wojtek Wiercioch; Yuan Zhang; Yuqing Zhang
Journal:  Blood Adv       Date:  2020-10-13

Review 8.  Prognostic models in acute pulmonary embolism: a systematic review and meta-analysis.

Authors:  Antoine Elias; Susan Mallett; Marie Daoud-Elias; Jean-Noël Poggi; Mike Clarke
Journal:  BMJ Open       Date:  2016-04-29       Impact factor: 2.692

Review 9.  A systematic review to identify and assess the effectiveness of alternatives for people over the age of 65 who are at risk of potentially avoidable hospital admission.

Authors:  Alyson L Huntley; Melanie Chalder; Ali R G Shaw; William Hollingworth; Chris Metcalfe; Jonathan Richard Benger; Sarah Purdy
Journal:  BMJ Open       Date:  2017-08-01       Impact factor: 2.692

10.  Acute Pulmonary Embolism in Emergency Department Patients Despite Therapeutic Anticoagulation.

Authors:  Michelle Y Liu; Dustin W Ballard; Jie Huang; Adina S Rauchwerger; Mary E Reed; Sean C Bouvet; David R Vinson
Journal:  West J Emerg Med       Date:  2018-04-06
  10 in total

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