Literature DB >> 19782409

Making a neuron: Cdk5 in embryonic and adult neurogenesis.

Sebastian Jessberger1, Fred H Gage, Amelia J Eisch, Diane C Lagace.   

Abstract

Cyclin-dependent kinase 5 (Cdk5) has been implicated in the migration, maturation and survival of neurons born during embryonic development. New evidence suggests that Cdk5 has comparable but also distinct functions in adult neurogenesis. Here we summarize accumulating evidence on the role of Cdk5 in regulation of the cell cycle, migration, survival, maturation and neuronal integration. We specifically highlight the many similarities and few tantalizing differences in the roles of Cdk5 in the embryonic and adult brain. We discuss the signaling pathways that might contribute to Cdk5 action in regulating embryonic and adult neurogenesis, highlighting future research directions that will help to clarify the mechanisms underlying lifelong neurogenesis in the mammalian brain.

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Year:  2009        PMID： 19782409      PMCID： PMC2767479          DOI： 10.1016/j.tins.2009.07.002

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  84 in total

Review 1.  The centrosome in neuronal development.

Authors:  Holden R Higginbotham; Joseph G Gleeson
Journal:  Trends Neurosci       Date:  2007-04-08       Impact factor: 13.837

2.  Synapse formation on neurons born in the adult hippocampus.

Authors:  Nicolas Toni; E Matthew Teng; Eric A Bushong; James B Aimone; Chunmei Zhao; Antonella Consiglio; Henriette van Praag; Maryann E Martone; Mark H Ellisman; Fred H Gage
Journal:  Nat Neurosci       Date:  2007-05-07       Impact factor: 24.884

3.  Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain.

Authors:  Xin Duan; Jay H Chang; Shaoyu Ge; Regina L Faulkner; Ju Young Kim; Yasuji Kitabatake; Xiao-bo Liu; Chih-Hao Yang; J Dedrick Jordan; Dengke K Ma; Cindy Y Liu; Sundar Ganesan; Hwai-Jong Cheng; Guo-li Ming; Bai Lu; Hongjun Song
Journal:  Cell       Date:  2007-09-06       Impact factor: 41.582

4.  Dynamic contribution of nestin-expressing stem cells to adult neurogenesis.

Authors:  Diane C Lagace; Mary C Whitman; Michele A Noonan; Jessica L Ables; Nathan A DeCarolis; Amy A Arguello; Michael H Donovan; Stephanie J Fischer; Laure A Farnbauch; Robert D Beech; Ralph J DiLeone; Charles A Greer; Chitra D Mandyam; Amelia J Eisch
Journal:  J Neurosci       Date:  2007-11-14       Impact factor: 6.167

5.  Cyclin-dependent kinase 5 is required for control of neuroblast migration in the postnatal subventricular zone.

Authors:  Yuki Hirota; Toshio Ohshima; Naoko Kaneko; Makiko Ikeda; Takuji Iwasato; Ashok B Kulkarni; Katsuhiko Mikoshiba; Hideyuki Okano; Kazunobu Sawamoto
Journal:  J Neurosci       Date:  2007-11-21       Impact factor: 6.167

6.  Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease.

Authors:  Dianbo Qu; Juliet Rashidian; Matthew P Mount; Hossein Aleyasin; Mohammad Parsanejad; Arman Lira; Emdadul Haque; Yi Zhang; Steve Callaghan; Mireille Daigle; Maxime W C Rousseaux; Ruth S Slack; Paul R Albert; Inez Vincent; John M Woulfe; David S Park
Journal:  Neuron       Date:  2007-07-05       Impact factor: 17.173

Review 7.  The roles of cyclin-dependent kinase 5 in dendrite and synapse development.

Authors:  Zelda H Cheung; Nancy Y Ip
Journal:  Biotechnol J       Date:  2007-08       Impact factor: 4.677

8.  Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation.

Authors:  Ammar H Hawasli; David R Benavides; Chan Nguyen; Janice W Kansy; Kanehiro Hayashi; Pierre Chambon; Paul Greengard; Craig M Powell; Donald C Cooper; James A Bibb
Journal:  Nat Neurosci       Date:  2007-05-27       Impact factor: 24.884

9.  Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex.

Authors:  Toshio Ohshima; Motoyuki Hirasawa; Hidenori Tabata; Tetsuji Mutoh; Tomoko Adachi; Hiromi Suzuki; Keiko Saruta; Takuji Iwasato; Shigeyoshi Itohara; Mistuhiro Hashimoto; Kazunori Nakajima; Masaharu Ogawa; Ashok B Kulkarni; Katsuhiko Mikoshiba
Journal:  Development       Date:  2007-05-16       Impact factor: 6.868

10.  Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons.

Authors:  Zelda H Cheung; Wing Hong Chin; Yu Chen; Yu Pong Ng; Nancy Y Ip
Journal:  PLoS Biol       Date:  2007-04       Impact factor: 8.029
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  45 in total

Review 1.  Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind.

Authors:  Jenny Hsieh; Amelia J Eisch
Journal:  Neurobiol Dis       Date:  2010-01-28       Impact factor: 5.996

2.  Effect of GAPT extract on expression of tau protein and its phosphorylation related enzymes in hippocampal neurons of APPV717I transgenic mice.

Authors:  Jing-Nian Ni; Jing Shi; Xue-Kai Zhang; Yi-Chang Yang; Xiao-Meng Liu; Ming-Qing Wei; Ting Li; Peng-Wen Wang; Jin-Zhou Tian; Yong-Yan Wang
Journal:  Chin J Integr Med       Date:  2017-06-20       Impact factor: 1.978

Review 3.  Cell cycle regulation during neurogenesis in the embryonic and adult brain.

Authors:  Arquimedes Cheffer; Attila Tárnok; Henning Ulrich
Journal:  Stem Cell Rev Rep       Date:  2013-12       Impact factor: 5.739

4.  Discovery of thienoquinolone derivatives as selective and ATP non-competitive CDK5/p25 inhibitors by structure-based virtual screening.

Authors:  Arindam Chatterjee; Stephen J Cutler; Robert J Doerksen; Ikhlas A Khan; John S Williamson
Journal:  Bioorg Med Chem       Date:  2014-09-28       Impact factor: 3.641

5.  CDK5-Mediated Phosphorylation-Dependent Ubiquitination and Degradation of E3 Ubiquitin Ligases GP78 Accelerates Neuronal Death in Parkinson's Disease.

Authors:  Qingzhi Wang; Fengjuan Jiao; Pei Zhang; Jianguo Yan; Zheng Zhang; Feng He; Qian Zhang; Zexi Lv; Xiang Peng; Hongwei Cai; Bo Tian
Journal:  Mol Neurobiol       Date:  2017-05-20       Impact factor: 5.590

6.  Multitrait meta-analysis identified genomic regions associated with sexual precocity in tropical beef cattle.

Authors:  Thaise P Melo; Marina R S Fortes; Tiago Bresolin; Lucio F M Mota; Lucia G Albuquerque; Roberto Carvalheiro
Journal:  J Anim Sci       Date:  2018-09-29       Impact factor: 3.159

7.  Identification of a neuronal gene expression signature: role of cell cycle arrest in murine neuronal differentiation in vitro.

Authors:  Hady Felfly; Jin Xue; Alexander C Zambon; Alysson Muotri; Dan Zhou; Gabriel G Haddad
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-06-15       Impact factor: 3.619

Review 8.  Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders.

Authors:  Jerel Adam Fields; Wilmar Dumaop; Leslie Crews; Anthony Adame; Brian Spencer; Jeff Metcalf; Johnny He; Edward Rockenstein; Eliezer Masliah
Journal:  Curr HIV Res       Date:  2015       Impact factor: 1.581

9.  Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.

Authors:  Gretchen Kusek; Melissa Campbell; Frank Doyle; Scott A Tenenbaum; Michael Kiebler; Sally Temple
Journal:  Cell Stem Cell       Date:  2012-08-16       Impact factor: 24.633

10.  Functional characterization of CDK5 and CDK5R1 mutations identified in patients with non-syndromic intellectual disability.

Authors:  Silvia Moncini; Paola Castronovo; Alessandra Murgia; Silvia Russo; Maria Francesca Bedeschi; Marta Lunghi; Angelo Selicorni; Maria Teresa Bonati; Paola Riva; Marco Venturin
Journal:  J Hum Genet       Date:  2015-12-10       Impact factor: 3.172
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