Literature DB >> 19781750

Rigorous bicycling does not increase serum levels of total and free prostate-specific antigen (PSA), the free/total PSA ratio, gonadotropin levels, or uroflowmetric parameters.

Tolga Saka1, Mustafa Sofikerim, Abdullah Demirtas, Sevsen Kulaksizoglu, Mehmet Caniklioglu, Mustafa Karacagil.   

Abstract

OBJECTIVES: To determine whether cycling has an effect on serum PSA, gonadotropins, and uroflowmetric parameters.
METHODS: A total of 34 healthy male athletes from the National Cycling Team and 24 healthy male student volunteers from University and medical staff were prospectively enrolled in the study. Blood samples for serum total prostate-specific antigen (tPSA), free PSA (fPSA, fPSA/tPSA, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone determinations were obtained before and after cyclists completed 300 km bicycle ride and with each cyclist seated without changing posture and with minimal movement for 10 minutes before blood collection. The cyclists also performed uroflowmetric and postvoid residual urine volume analysis before, and 1 hour after cycling course. Blood samples from the control group were drawn for serum hormones. They also underwent uroflowmetric and postvoid residual analysis.
RESULTS: The athletes and the control group were well matched by age. There was no significant difference between the 2 groups in terms of serum tPSA, fPSA, f/t PSA values, FSH, LH, and testosterone levels and uroflowmetric parameters (P >.05). The differences between pre- and postcycling values for tPSA, fPSA, f/t PSA, FSH, LH, and uroflowmetric parameters were not statistically significant. The postcycling serum testosterone level was significantly lower than precycling levels (mean, 603.6 ng/dL [range, 300-949] vs 424.8 ng/dL [range, 193-723], P = .001]. There was no correlation between body mass index values, postcycling serum FSH, LH levels, age, and testosterone levels.
CONCLUSIONS: There is no effect of professional bicycle riding on serum total and fPSA levels and uroflowmetric parameters.

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Year:  2009        PMID: 19781750     DOI: 10.1016/j.urology.2009.07.1219

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  7 in total

Review 1.  The effect of bicycling on PSA levels: a systematic review and meta-analysis.

Authors:  D Jiandani; A Randhawa; R E Brown; R Hamilton; A G Matthew; J L Kuk; S M H Alibhai; E Tufts; D Santa Mina
Journal:  Prostate Cancer Prostatic Dis       Date:  2015-05-05       Impact factor: 5.554

2.  [Influencing of the PSA concentration in serum by physical exercise (especially bicycle riding)].

Authors:  W Kindermann; V Lehmann; M Herrmann; T Loch
Journal:  Urologe A       Date:  2011-02       Impact factor: 0.639

Review 3.  Exercise, Training, and the Hypothalamic-Pituitary-Gonadal Axis in Men and Women.

Authors:  Natalia Cano Sokoloff; Madhusmita Misra; Kathryn E Ackerman
Journal:  Front Horm Res       Date:  2016-06-27       Impact factor: 2.606

4.  Long distance bicycle riding causes prostate-specific antigen to increase in men aged 50 years and over.

Authors:  Sandra L Mejak; Julianne Bayliss; Shayne D Hanks
Journal:  PLoS One       Date:  2013-02-13       Impact factor: 3.240

5.  Does bicycle riding impact the development of lower urinary tract symptoms and sexual dysfunction in men?

Authors:  Dong Gon Kim; Dae Woong Kim; Jong Kwan Park
Journal:  Korean J Urol       Date:  2011-05-24

6.  Is Cycling Practice Related to Men's Pelvic Floor Dysfunctions? A Hypothesis-Generating Observational Study.

Authors:  Guadalupe Molina-Torres; Mirari Ochandorena-Acha; Yune Echazarreta-Aparicio; Nuria Sánchez-Labraca; Manuel González-Sánchez; Marc Terradas-Monllor; Luz A Varela-Vásquez; Jose Antonio Merchán-Baeza; Eduard Minobes-Molina
Journal:  Int J Environ Res Public Health       Date:  2021-02-17       Impact factor: 3.390

7.  Influence of Long-Distance Bicycle Riding on Serum/Urinary Biomarkers of Prostate Cancer.

Authors:  Zbynek Heger; Jaromir Gumulec; Ales Ondrak; Jan Skoda; Zdenek Zitka; Natalia Cernei; Michal Masarik; Ondrej Zitka; Vojtech Adam
Journal:  Int J Mol Sci       Date:  2016-03-17       Impact factor: 5.923

  7 in total

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