| Literature DB >> 1978164 |
K Vijayaraghavan1, G Radhaiah, B S Prakasam, K V Sarma, V Reddy.
Abstract
The effect of vitamin A supplementation on preschool child morbidity and mortality was assessed in a prospective double-blind placebo-controlled study around Hyderabad, India. Every six months 200,000 IU vitamin A was given to 7691 children (treatment group) whereas 8084 children received a placebo (control group). Morbidity and mortality data were collected every three months. Risk of respiratory infection was higher in children with mild xerophthalmia than in children with normal eyes. Vitamin A supplementation had no effect on morbidity status. Mortality rates were similar in the two groups; it was highest in children who did not receive either vitamin A or placebo. The findings suggest that vitamin A supplementation alone may not reduce child mortality.Entities:
Keywords: Age Distribution; Age Factors; Asia; Biology; Child Mortality; Demographic Factors; Developing Countries; Diseases; Double-blind Studies; India; Measurement; Morbidity; Mortality; Ophthalmological Effects; Physiology; Population; Population Characteristics; Population Dynamics; Prevalence; Prospective Studies; Research Methodology; Rural Population; Sex Distribution; Sex Factors; Southern Asia; Studies; Vitamin A--administraction and dosage; Vitamins
Mesh：
Substances：
Year: 1990 PMID： 1978164 DOI： 10.1016/0140-6736(90)92895-o
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321