OBJECTIVE: Evaluation of a dietary Na reduction trial in a community setting. DESIGN: Community-based randomized trial. Ten-week nutrition intervention activities focused on lifestyle modification to decrease dietary Na intake, under the supervision of a registered dietitian. Twenty-four hour urine specimens were collected at baseline and follow-up visits to determine 24 h urinary Na excretion. SETTING: The University of Pittsburgh Center for Healthy Aging, Key to Life Nutrition Program. SUBJECTS:Hypertensive adults at least 65 years of age. RESULTS:Mean age of participants was 75 years. Twenty-four hour mean urinary Na excretion at baseline was 3174 mg/d. This reduced to 2944 mg/d (P = 0.30) and 2875 mg/d (P <or= 0.03) at 6- and 12-month follow-ups, respectively. In a sub-sample (urine volume of >or=1000 ml, baseline to 12 months), mean urinary Na excretion decreased from 3220 mg/d to 2875 mg/d (P <or= 0.02). CONCLUSIONS: Significant reductions in mean 24 h urinary Na were reported, but results fell short of the recommended guidelines of 1500 mg/d for at-risk individuals. Our results reiterate the difficulty in implementing these guidelines in community-based programmes. More aggressive public health efforts, food industry support and health policy changes are needed to decrease Na levels in older adults to the recommended guidelines.
RCT Entities:
OBJECTIVE: Evaluation of a dietary Na reduction trial in a community setting. DESIGN: Community-based randomized trial. Ten-week nutrition intervention activities focused on lifestyle modification to decrease dietary Na intake, under the supervision of a registered dietitian. Twenty-four hour urine specimens were collected at baseline and follow-up visits to determine 24 h urinary Na excretion. SETTING: The University of Pittsburgh Center for Healthy Aging, Key to Life Nutrition Program. SUBJECTS:Hypertensive adults at least 65 years of age. RESULTS: Mean age of participants was 75 years. Twenty-four hour mean urinary Na excretion at baseline was 3174 mg/d. This reduced to 2944 mg/d (P = 0.30) and 2875 mg/d (P <or= 0.03) at 6- and 12-month follow-ups, respectively. In a sub-sample (urine volume of >or=1000 ml, baseline to 12 months), mean urinary Na excretion decreased from 3220 mg/d to 2875 mg/d (P <or= 0.02). CONCLUSIONS: Significant reductions in mean 24 h urinary Na were reported, but results fell short of the recommended guidelines of 1500 mg/d for at-risk individuals. Our results reiterate the difficulty in implementing these guidelines in community-based programmes. More aggressive public health efforts, food industry support and health policy changes are needed to decrease Na levels in older adults to the recommended guidelines.
Authors: Lawrence J Appel; Catherine M Champagne; David W Harsha; Lawton S Cooper; Eva Obarzanek; Patricia J Elmer; Victor J Stevens; William M Vollmer; Pao-Hwa Lin; Laura P Svetkey; Sarah W Stedman; Deborah R Young Journal: JAMA Date: 2003 Apr 23-30 Impact factor: 56.272
Authors: Anne B Newman; Constance M Bayles; Carole N Milas; Kathleen McTigue; Kathy Williams; Joseph F Robare; Christopher A Taylor; Stephen M Albert; Lewis H Kuller Journal: J Aging Health Date: 2010-05-21
Authors: Aram V Chobanian; George L Bakris; Henry R Black; William C Cushman; Lee A Green; Joseph L Izzo; Daniel W Jones; Barry J Materson; Suzanne Oparil; Jackson T Wright; Edward J Roccella Journal: Hypertension Date: 2003-12-01 Impact factor: 10.190
Authors: Maya N Clark-Cutaia; Dianxu Ren; Leslie A Hoffman; Linda Snetselaar; Mary Ann Sevick Journal: Top Clin Nutr Date: 2013 Oct-Dec Impact factor: 0.508
Authors: Lirije Hyseni; Alex Elliot-Green; Ffion Lloyd-Williams; Chris Kypridemos; Martin O'Flaherty; Rory McGill; Lois Orton; Helen Bromley; Francesco P Cappuccio; Simon Capewell Journal: PLoS One Date: 2017-05-18 Impact factor: 3.240