BACKGROUND: In several non-randomised trials training with EPI-NO increased the rate of intact perineum and decreased episiotomy rates, shortened the second stage of labour and lowered use of pain killers. AIMS: To verify the preliminary results with EPI-NO in a prospective randomised trial. METHODS: Randomised, single-blind multicentre trial in four university hospitals in Germany including 276 primigravidae. RESULTS: After training with EPI-NO we observed a significant increase in the incidence of intact perineum (37.4% vs 25.7%; P = 0.05) and a tendency towards lower episiotomy rates (41.9% vs 50.5%; P = 0.11). We found no significant differences between the two groups regarding incidence of perineal tears, duration of second stage of labour, use of pain relief and rate of vaginal infection. CONCLUSIONS: Training with EPI-NO increases significantly the likelihood of having an intact perineum and reduces the episiotomy rate.
RCT Entities:
BACKGROUND: In several non-randomised trials training with EPI-NO increased the rate of intact perineum and decreased episiotomy rates, shortened the second stage of labour and lowered use of pain killers. AIMS: To verify the preliminary results with EPI-NO in a prospective randomised trial. METHODS: Randomised, single-blind multicentre trial in four university hospitals in Germany including 276 primigravidae. RESULTS: After training with EPI-NO we observed a significant increase in the incidence of intact perineum (37.4% vs 25.7%; P = 0.05) and a tendency towards lower episiotomy rates (41.9% vs 50.5%; P = 0.11). We found no significant differences between the two groups regarding incidence of perineal tears, duration of second stage of labour, use of pain relief and rate of vaginal infection. CONCLUSIONS: Training with EPI-NO increases significantly the likelihood of having an intact perineum and reduces the episiotomy rate.
Authors: T Aigmueller; W Bader; K Beilecke; K Elenskaia; A Frudinger; E Hanzal; H Helmer; H Huemer; M van der Kleyn; D Koelle; S Kropshofer; J Pfeiffer; C Reisenauer; A Tammaa; K Tamussino; W Umek Journal: Geburtshilfe Frauenheilkd Date: 2015-02 Impact factor: 2.915
Authors: T Aigmueller; W Umek; K Elenskaia; A Frudinger; J Pfeifer; H Helmer; H Huemer; A Tammaa; M van der Kleyn; K Tamussino; D Koelle Journal: Int Urogynecol J Date: 2012-11-17 Impact factor: 2.894
Authors: Síssi Sisconeto de Freitas; Alana Leandro Cabral; Rogério de Melo Costa Pinto; Ana Paula Magalhães Resende; Vanessa Santos Pereira Baldon Journal: Int Urogynecol J Date: 2018-10-20 Impact factor: 2.894
Authors: Carla Dellabarba Petricelli; Ana Paula Magalhães Resende; Julio Elito Júnior; Edward Araujo Júnior; Sandra Maria Alexandre; Miriam Raquel Diniz Zanetti; Mary Uchiyama Nakamura Journal: Biomed Res Int Date: 2014-04-28 Impact factor: 3.411
Authors: Mary Uchiyama Nakamura; Nelson Sass; Julio Elito Júnior; Carla Dellabarba Petricelli; Sandra Maria Alexandre; Edward Araujo Júnior; Miriam Raquel Diniz Zanetti Journal: Einstein (Sao Paulo) Date: 2014 Jan-Mar