Literature DB >> 197775

Dense core vesicles around the Lewy body in incidental Parkinson's disease: an electron microscopic study.

I Watanabe, E Vachal, T Tomita.   

Abstract

In a case of Lewy body disease incidentally found at autopsy, numerous dense core vesicles 80--200 nm in diameter, were seen in the neuronal perikarya of the locus caeruleus. They were particularly numerous in the vicinity of the Lewy bodies. The change seems to occur at the early stage of Lewy body production and may represent an additional morphologic clue to abnormal catecholamine metabolism in Parkinson's disease.

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Mesh：

Year:  1977        PMID： 197775     DOI： 10.1007/bf00703325

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  7 in total

1.  The distribution of Lewy bodies in the central and autonomic nervous systems in idiopathic paralysis agitans.

Authors:  W A den HARTOG JAGER; J BETHLEM
Journal:  J Neurol Neurosurg Psychiatry       Date:  1960-11       Impact factor: 10.154

2.  Cytoplasmic inclusions in ganglion cells associated with parkinsonian states: a neurocellular change studied in 53 cases and 206 controls.

Authors:  L E LIPKIN
Journal:  Am J Pathol       Date:  1959 Nov-Dec       Impact factor: 4.307

3.  The brain-stem lesions in Parkinsonism.

Authors:  J G GREENFIELD; F D BOSANQUET
Journal:  J Neurol Neurosurg Psychiatry       Date:  1953-11       Impact factor: 10.154

4.  Concentric hyalin intraneuronal inclusions of Lewy type in the brains of elderly persons (50 incidental cases): relationship to parkinsonism.

Authors:  L S Forno
Journal:  J Am Geriatr Soc       Date:  1969-06       Impact factor: 5.562

5.  Shy-Drager syndrome. Report of an autopsied case.

Authors:  I M Thapedi; E M Ashenhurst; B Rozdilsky
Journal:  Neurology       Date:  1971-01       Impact factor: 9.910

6.  Ultrastructural observations in Parkinsonism.

Authors:  S Roy; L Wolman
Journal:  J Pathol       Date:  1969-09       Impact factor: 7.996

7.  Ultrastructure of Lewy bodies in the stellate ganglion.

Authors:  L S Forno; R L Norville
Journal:  Acta Neuropathol       Date:  1976-03-30       Impact factor: 17.088
  7 in total
  12 in total

1.  Aggregation of α-synuclein in S. cerevisiae is associated with defects in endosomal trafficking and phospholipid biosynthesis.

Authors:  James H Soper; Victoria Kehm; Christopher G Burd; Vytas A Bankaitis; Virginia M-Y Lee
Journal:  J Mol Neurosci       Date:  2010-10-02       Impact factor: 3.444

2.  Female Sex and Brain-Selective Estrogen Benefit α-Synuclein Tetramerization and the PD-like Motor Syndrome in 3K Transgenic Mice.

Authors:  Molly M Rajsombath; Alice Y Nam; Maria Ericsson; Silke Nuber
Journal:  J Neurosci       Date:  2019-08-12       Impact factor: 6.167

Review 3.  Reverse engineering Lewy bodies: how far have we come and how far can we go?

Authors:  Mohamed Bilal Fares; Somanath Jagannath; Hilal A Lashuel
Journal:  Nat Rev Neurosci       Date:  2021-01-11       Impact factor: 34.870

4.  An early cytoplasmic change before Lewy body maturation: an ultrastructural study of the substantia nigra from an autopsy case of juvenile parkinsonism.

Authors:  K Hayashida; S Oyanagi; Y Mizutani; M Yokochi
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

5.  Atypical senile dementia with widespread Lewy type inclusion in the cerebral cortex.

Authors:  S Yagishita; Y Itoh; N Amano; T Nakano
Journal:  Acta Neuropathol       Date:  1980       Impact factor: 17.088

6.  Suppression of α-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context.

Authors:  Vicente Sancenon; Sue-Ann Lee; Christina Patrick; Janice Griffith; Amy Paulino; Tiago F Outeiro; Fulvio Reggiori; Eliezer Masliah; Paul J Muchowski
Journal:  Hum Mol Genet       Date:  2012-02-21       Impact factor: 6.150

7.  The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis.

Authors:  Aaron D Gitler; Brooke J Bevis; James Shorter; Katherine E Strathearn; Shusei Hamamichi; Linhui Julie Su; Kim A Caldwell; Guy A Caldwell; Jean-Christophe Rochet; J Michael McCaffery; Charles Barlowe; Susan Lindquist
Journal:  Proc Natl Acad Sci U S A       Date:  2007-12-27       Impact factor: 11.205

8.  Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes.

Authors:  Laura A Volpicelli-Daley; Karen L Gamble; Christine E Schultheiss; Dawn M Riddle; Andrew B West; Virginia M-Y Lee
Journal:  Mol Biol Cell       Date:  2014-10-08       Impact factor: 4.138

Review 9.  Current concepts and controversies in the pathogenesis of Parkinson's disease dementia and Dementia with Lewy Bodies.

Authors:  Rimona S Weil; Tammaryn L Lashley; Jose Bras; Anette E Schrag; Jonathan M Schott
Journal:  F1000Res       Date:  2017-08-30

10.  Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease.

Authors:  Silke Nuber; Molly Rajsombath; Georgia Minakaki; Jürgen Winkler; Christian P Müller; Maria Ericsson; Barbara Caldarone; Ulf Dettmer; Dennis J Selkoe
Journal:  Neuron       Date:  2018-10-10       Impact factor: 17.173
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