| Literature DB >> 1977738 |
Abstract
In Escherichia coli, genes aroF+, aroG+, and aroH+ encode isoenzymes of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that are feedback inhibited by tyrosine, phenylalanine, and tryptophan, respectively. A single base pair change in aroF causes a Pro-148-to-Leu-148 substitution and results in a tyrosine-insensitive enzyme.Entities:
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Year: 1990 PMID: 1977738 PMCID: PMC526849 DOI: 10.1128/jb.172.11.6581-6584.1990
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490