Literature DB >> 1977688

The human aminopeptidase N gene: isolation, chromosome localization, and DNA polymorphism analysis.

V M Watt1, H F Willard.   

Abstract

DNA encoding the human aminopeptidase N (EC 3.4.11.2) gene (PEPN) was first isolated using rat cDNA probes and then used in Southern analysis of DNA from mouse-human somatic cell hybrids to assign this gene to the long-arm region (q11-qter) of human chromosome 15. This human genomic DNA probe detects a frequent DraIII polymorphism that is a useful marker for human chromosome 15.

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Year:  1990        PMID： 1977688     DOI： 10.1007/bf00193592

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  29 in total

1.  Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA.

Authors:  J Olsen; G M Cowell; E Kønigshøfer; E M Danielsen; J Møller; L Laustsen; O C Hansen; K G Welinder; J Engberg; W Hunziker
Journal:  FEBS Lett       Date:  1988-10-10       Impact factor: 4.124

2.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

3.  Cloning of the pig aminopeptidase N gene. Identification of possible regulatory elements and the exon distribution in relation to the membrane-spanning region.

Authors:  J Olsen; H Sjöström; O Norén
Journal:  FEBS Lett       Date:  1989-07-17       Impact factor: 4.124

4.  Fast-twitch and slow-twitch/cardiac Ca2+ ATPase genes map to human chromosomes 16 and 12.

Authors:  D H MacLennan; C J Brandl; S Champaneria; P C Holland; V E Powers; H F Willard
Journal:  Somat Cell Mol Genet       Date:  1987-07

5.  Molecular cloning, expression, and chromosomal localization of the gene encoding a human myeloid membrane antigen (gp150).

Authors:  A T Look; S C Peiper; M B Rebentisch; R A Ashmun; M F Roussel; R S Lemons; M M Le Beau; C M Rubin; C J Sherr
Journal:  J Clin Invest       Date:  1986-10       Impact factor: 14.808

Review 6.  Urinary enzymes, nephrotoxicity and renal disease.

Authors:  R G Price
Journal:  Toxicology       Date:  1982       Impact factor: 4.221

7.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

8.  Amino acid sequence deduced from a rat kidney cDNA suggests it encodes the Zn-peptidase aminopeptidase N.

Authors:  V M Watt; C C Yip
Journal:  J Biol Chem       Date:  1989-04-05       Impact factor: 5.157

9.  The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

Authors:  R M Lawn; E F Fritsch; R C Parker; G Blake; T Maniatis
Journal:  Cell       Date:  1978-12       Impact factor: 41.582

10.  Human beta-hexosaminidase alpha chain: coding sequence and homology with the beta chain.

Authors:  R Myerowitz; R Piekarz; E F Neufeld; T B Shows; K Suzuki
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205
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  11 in total

1.  The Drosophila slamdance gene: a mutation in an aminopeptidase can cause seizure, paralysis and neuronal failure.

Authors:  HaiGuang Zhang; Jeff Tan; Elaine Reynolds; Daniel Kuebler; Sally Faulhaber; Mark Tanouye
Journal:  Genetics       Date:  2002-11       Impact factor: 4.562

2.  Induction of the membrane alanyl aminopeptidase gene and surface expression in human T-cells by mitogenic activation.

Authors:  U Lendeckel; T Wex; D Reinhold; T Kähne; K Frank; J Faust; K Neubert; S Ansorge
Journal:  Biochem J       Date:  1996-11-01       Impact factor: 3.857

3.  Rapid mitogen-induced aminopeptidase N surface expression in human T cells is dominated by mechanisms independent of de novo protein biosynthesis.

Authors:  U Lendeckel; T Wex; A Ittenson; M Arndt; K Frank; O Mayboroda; W Schubert; S Ansorge
Journal:  Immunobiology       Date:  1997-06       Impact factor: 3.144

4.  High aminopeptidase N/CD13 levels characterize human amniotic mesenchymal stem cells and drive their increased adipogenic potential in obese women.

Authors:  Laura Iaffaldano; Carmela Nardelli; Maddalena Raia; Elisabetta Mariotti; Maddalena Ferrigno; Filomena Quaglia; Giuseppe Labruna; Valentina Capobianco; Angela Capone; Giuseppe Maria Maruotti; Lucio Pastore; Rosa Di Noto; Pasquale Martinelli; Lucia Sacchetti; Luigi Del Vecchio
Journal:  Stem Cells Dev       Date:  2013-04-23       Impact factor: 3.272

5.  Involvement of aminopeptidase N (CD13) in infection of human neural cells by human coronavirus 229E.

Authors:  C Lachance; N Arbour; N R Cashman; P J Talbot
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

6.  Allelic expression imbalance: tipping the scales to elucidate the function of type 2 diabetes-associated loci.

Authors:  Shana E McCormack; Struan F A Grant
Journal:  Diabetes       Date:  2015-04       Impact factor: 9.461

7.  Extracellular cysteines define ectopeptidase (APN, CD13) expression and function.

Authors:  Beate Firla; Marco Arndt; Karin Frank; Ute Thiel; Siegfried Ansorge; Michael Täger; Uwe Lendeckel
Journal:  Free Radic Biol Med       Date:  2002-04-01       Impact factor: 7.376

Review 8.  Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects.

Authors:  Brigitte Bauvois; Daniel Dauzonne
Journal:  Med Res Rev       Date:  2006-01       Impact factor: 12.944

Review 9.  The significance of aminopeptidases and haematopoietic cell differentiation.

Authors:  K Razak; A C Newland
Journal:  Blood Rev       Date:  1992-12       Impact factor: 8.250

Review 10.  The moonlighting enzyme CD13: old and new functions to target.

Authors:  Paola Mina-Osorio
Journal:  Trends Mol Med       Date:  2008-07-05       Impact factor: 11.951
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