Suk Keu Yeom1, Hye Jin Kim, Jae Ho Byun, Ah Young Kim, Moon-Gyu Lee, Hyun Kwon Ha. 1. Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap2-dong, Songpa-gu, Seoul 138-736, Republic of Korea. pagoda20@hanmail.net
Abstract
OBJECTIVE: In order to retrospectively evaluate the CT findings of abdominal aspergillosis in immunocompromised patients. MATERIALS AND METHODS: CT scans were reviewed with regard to the sites, number, morphologic appearance, attenuation, and the contrast enhancement patterns of the lesions in six patients (5 women, 1 man; mean age, 43.4 years; range, 23-59 years) with pathologically proved abdominal aspergillosis by two gastrointestinal radiologists in consensus. Medical records were also reviewed to determine each patient's clinical status and outcome. RESULTS: All patients were immunocompromised state: 4 patients received immunosuppressive therapy for solid organ transplantation and 2 patients received chemotherapy for acute myeloid leukemia. Aspergillosis involved blood vessels (n = 3), liver (n = 2), spleen (n = 2), gastrointestinal tract (n = 2), native kidney (n = 1), transplanted kidney (n = 1), peritoneum (n = 1), and retroperitoneum (n = 1). CT demonstrated solid organ or bowel infarction or perforation secondary to vascular thrombosis or pseudoaneurysm, multiple low-attenuating lesions of solid organs presenting as abscesses, concentric bowel wall thickening mimicking typhlitis, or diffuse or nodular infiltration of the peritoneum and retroperitoneum. CONCLUSION: Familiarity with findings commonly presenting as angioinvasive features or abscesses on CT, may facilitate the diagnosis of rare and fatal abdominal aspergillosis.
OBJECTIVE: In order to retrospectively evaluate the CT findings of abdominal aspergillosis in immunocompromised patients. MATERIALS AND METHODS: CT scans were reviewed with regard to the sites, number, morphologic appearance, attenuation, and the contrast enhancement patterns of the lesions in six patients (5 women, 1 man; mean age, 43.4 years; range, 23-59 years) with pathologically proved abdominal aspergillosis by two gastrointestinal radiologists in consensus. Medical records were also reviewed to determine each patient's clinical status and outcome. RESULTS: All patients were immunocompromised state: 4 patients received immunosuppressive therapy for solid organ transplantation and 2 patients received chemotherapy for acute myeloid leukemia. Aspergillosis involved blood vessels (n = 3), liver (n = 2), spleen (n = 2), gastrointestinal tract (n = 2), native kidney (n = 1), transplanted kidney (n = 1), peritoneum (n = 1), and retroperitoneum (n = 1). CT demonstrated solid organ or bowel infarction or perforation secondary to vascular thrombosis or pseudoaneurysm, multiple low-attenuating lesions of solid organs presenting as abscesses, concentric bowel wall thickening mimicking typhlitis, or diffuse or nodular infiltration of the peritoneum and retroperitoneum. CONCLUSION: Familiarity with findings commonly presenting as angioinvasive features or abscesses on CT, may facilitate the diagnosis of rare and fatal abdominal aspergillosis.
Authors: Malak Itani; Christine O Menias; Vincent M Mellnick; Aline El Zakhem; Khaled Elsayes; Venkata Katabathina; Margarita V Revzin Journal: Abdom Radiol (NY) Date: 2021-01-02
Authors: Ali Devrim Karaosmanoglu; Aycan Uysal; Omer Onder; Peter F Hahn; Deniz Akata; Mustafa Nasuh Ozmen; Musturay Karcaaltıncaba Journal: Abdom Radiol (NY) Date: 2021-05-28