Literature DB >> 19775597

Bioactive flavones and biflavones from Selaginella moellendorffii Hieron.

Yuan Cao1, Nin-Hua Tan, Ji-Jun Chen, Guang-Zhi Zeng, Yun-Bao Ma, Yong-Ping Wu, He Yan, Jie Yang, Lai-Feng Lu, Qiang Wang.   

Abstract

Three new flavones named 5-carboxymethyl-4',7-dihydroxyflavone (1), its ethyl ester (2) and butyl ester (3) were isolated from the herb Selaginella moellendorffii Hieron., together with ten known compounds. Their structures were elucidated on the basis of spectroscopic and chemical analysis. Selected compounds were evaluated for their anti-HBV and cytotoxic activity. Among them, compounds 2 and 3 displayed inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with IC(50) values of 0.17 mg/ml and 0.46 mg/ml, and on HBV e antigen (HBeAg) secretion with IC(50) values of 0.42 mg/ml and 0.42 mg/ml, respectively. Compounds 7, 8, 10 and 12 exhibited selective cytotoxicity against the three human cancer cell lines tested. (c) 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID： 19775597     DOI： 10.1016/j.fitote.2009.09.007

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  18 in total

1.  The Selaginella genome identifies genetic changes associated with the evolution of vascular plants.

Authors:  Jo Ann Banks; Tomoaki Nishiyama; Mitsuyasu Hasebe; John L Bowman; Michael Gribskov; Claude dePamphilis; Victor A Albert; Naoki Aono; Tsuyoshi Aoyama; Barbara A Ambrose; Neil W Ashton; Michael J Axtell; Elizabeth Barker; Michael S Barker; Jeffrey L Bennetzen; Nicholas D Bonawitz; Clint Chapple; Chaoyang Cheng; Luiz Gustavo Guedes Correa; Michael Dacre; Jeremy DeBarry; Ingo Dreyer; Marek Elias; Eric M Engstrom; Mark Estelle; Liang Feng; Cédric Finet; Sandra K Floyd; Wolf B Frommer; Tomomichi Fujita; Lydia Gramzow; Michael Gutensohn; Jesper Harholt; Mitsuru Hattori; Alexander Heyl; Tadayoshi Hirai; Yuji Hiwatashi; Masaki Ishikawa; Mineko Iwata; Kenneth G Karol; Barbara Koehler; Uener Kolukisaoglu; Minoru Kubo; Tetsuya Kurata; Sylvie Lalonde; Kejie Li; Ying Li; Amy Litt; Eric Lyons; Gerard Manning; Takeshi Maruyama; Todd P Michael; Koji Mikami; Saori Miyazaki; Shin-ichi Morinaga; Takashi Murata; Bernd Mueller-Roeber; David R Nelson; Mari Obara; Yasuko Oguri; Richard G Olmstead; Naoko Onodera; Bent Larsen Petersen; Birgit Pils; Michael Prigge; Stefan A Rensing; Diego Mauricio Riaño-Pachón; Alison W Roberts; Yoshikatsu Sato; Henrik Vibe Scheller; Burkhard Schulz; Christian Schulz; Eugene V Shakirov; Nakako Shibagaki; Naoki Shinohara; Dorothy E Shippen; Iben Sørensen; Ryo Sotooka; Nagisa Sugimoto; Mamoru Sugita; Naomi Sumikawa; Milos Tanurdzic; Günter Theissen; Peter Ulvskov; Sachiko Wakazuki; Jing-Ke Weng; William W G T Willats; Daniel Wipf; Paul G Wolf; Lixing Yang; Andreas D Zimmer; Qihui Zhu; Therese Mitros; Uffe Hellsten; Dominique Loqué; Robert Otillar; Asaf Salamov; Jeremy Schmutz; Harris Shapiro; Erika Lindquist; Susan Lucas; Daniel Rokhsar; Igor V Grigoriev
Journal:  Science       Date:  2011-05-05       Impact factor: 47.728

2.  Candidate genes of flavonoid biosynthesis in Selaginella bryopteris (L.) Baker identified by RNA-Seq.

Authors:  Ravi S Singh; Ravi Kesari; Ujjwal Kumar; Vikash Kumar Jha; Anjani Kumar; Tribhuwan Kumar; Awadhesh K Pal; Prabhash K Singh
Journal:  Funct Integr Genomics       Date:  2018-04-18       Impact factor: 3.410

3.  In vitro anti-cancer activity of chamaejasmenin B and neochamaejasmin C isolated from the root of Stellera chamaejasme L.

Authors:  Chong Zhang; Shuang-shuang Zhou; Lin-yi Feng; Da-yong Zhang; Neng-ming Lin; Li-huang Zhang; Jian-ping Pan; Jun-bo Wang; Jie Li
Journal:  Acta Pharmacol Sin       Date:  2012-12-10       Impact factor: 6.150

4.  Application of the ITS2 Region for Barcoding Medicinal Plants of Selaginellaceae in Pteridophyta.

Authors:  Wei Gu; Jingyuan Song; Yuan Cao; Qingwen Sun; Hui Yao; Qinan Wu; Jianguo Chao; Juanjuan Zhou; Wenda Xue; Jinao Duan
Journal:  PLoS One       Date:  2013-06-27       Impact factor: 3.240

5.  Rapid Screening and Structural Characterization of Antioxidants from the Extract of Selaginella doederleinii Hieron with DPPH-UPLC-Q-TOF/MS Method.

Authors:  Gang Wang; Shun Yao; Xiu-Xiu Zhang; Hang Song
Journal:  Int J Anal Chem       Date:  2015-02-22       Impact factor: 1.885

6.  Deciphering the Molecular Mechanism Responsible for Efficiently Inhibiting Metastasis of Human Non-Small Cell Lung and Colorectal Cancer Cells Targeting the Matrix Metalloproteinases by Selaginella repanda.

Authors:  Mohd Adnan; Arif Jamal Siddiqui; Walid Sabri Hamadou; Mejdi Snoussi; Riadh Badraoui; Syed Amir Ashraf; Arshad Jamal; Amir Mahgoub Awadelkareem; Manojkumar Sachidanandan; Sibte Hadi; Mushtaq Ahmad Khan; Mitesh Patel
Journal:  Plants (Basel)       Date:  2021-05-14

7.  Antinociceptive effect of ethanolic extract of Selaginella convoluta in mice.

Authors:  Pedro Guilherme S de Sá; Xirley Pereira Nunes; Julianeli Tolentino de Lima; José Alves de Siqueira Filho; André Paviotti Fontana; Jullyana de Souza Siqueira; Lucindo José Quintans-Júnior; Patrícia Kauanna Fonseca Damasceno; Carla Rodrigues Cardoso Branco; Alexsandro Branco; Jackson Roberto Guedes da Silva Almeida
Journal:  BMC Complement Altern Med       Date:  2012-10-19       Impact factor: 3.659

8.  Chemodiversity in Selaginella: a reference system for parallel and convergent metabolic evolution in terrestrial plants.

Authors:  Jing-Ke Weng; Joseph P Noel
Journal:  Front Plant Sci       Date:  2013-05-10       Impact factor: 5.753

9.  Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring.

Authors:  Chao Yang; Yutian Shao; Kang Li; Wujiong Xia
Journal:  Beilstein J Org Chem       Date:  2012-11-05       Impact factor: 2.883

10.  Phosphoproteomic analysis of the non-seed vascular plant model Selaginella moellendorffii.

Authors:  Xi Chen; Wai Lung Chan; Fu-Yuan Zhu; Clive Lo
Journal:  Proteome Sci       Date:  2014-03-17       Impact factor: 2.480
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