| Literature DB >> 19775363 |
Abstract
Ultraviolet (UV) radiation is a complete carcinogen. The effects of UV radiation are mediated via direct damage to cellular DNA in the skin and suppression of image surveillance mechanisms. In the context of organ transplantation, addiction of drugs which suppress the immune system add greatly to the carcinogenicity of UV radiation. This review considers the mechanisms of such effects.Mesh:
Year: 2009 PMID: 19775363 DOI: 10.1111/j.1365-2133.2009.09455.x
Source DB: PubMed Journal: Br J Dermatol ISSN: 0007-0963 Impact factor: 9.302