Literature DB >> 19774242

Beta-amidoaldehydes via oxazoline hydroformylation.

David S Laitar1, John W Kramer, Bryan T Whiting, Emil B Lobkovsky, Geoffrey W Coates.   

Abstract

4-Substituted oxazolines, which are readily synthesized from naturally occurring alpha-amino acids, are converted efficiently and stereospecifically to beta-amidoaldehydes in the presence of synthesis gas and catalytic dicobalt octacarbonyl.

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Year:  2009        PMID: 19774242     DOI: 10.1039/b913698c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  KOt-Bu-promoted selective ring-opening N-alkylation of 2-oxazolines to access 2-aminoethyl acetates and N-substituted thiazolidinones.

Authors:  Qiao Lin; Shiling Zhang; Bin Li
Journal:  Beilstein J Org Chem       Date:  2020-03-25       Impact factor: 2.883

2.  Expanding the Scope of the Cleavable N-(methoxy)oxazolidine Linker for the Synthesis of Oligonucleotide Conjugates.

Authors:  Aapo Aho; Antti Äärelä; Heidi Korhonen; Pasi Virta
Journal:  Molecules       Date:  2021-01-18       Impact factor: 4.411

  2 in total

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