| Literature DB >> 19773611 |
Nadeem Sarwar1, Alexander J Thompson, Emanuele Di Angelantonio.
Abstract
Cardiovascular disease is the leading cause of global mortality, with coronary heart disease (CHD) its major manifestation. Although inflammation, the body's response to noxious stimuli, is implicated in several stages of CHD development, the relevance of circulating levels of markers of inflammation to CHD risk remains uncertain. This review summarizes available epidemiological evidence for four emerging inflammatory markers implicated in CHD (fibrinogen, C-reactive protein, lipoprotein-associated phospholipase A2 and interleukin-6); considers their likely utility in cardiovascular risk prediction; and outlines areas of outstanding uncertainty.Entities:
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Year: 2009 PMID: 19773611 PMCID: PMC3833412 DOI: 10.3233/DMA-2009-0646
Source DB: PubMed Journal: Dis Markers ISSN: 0278-0240 Impact factor: 3.434