OBJECTIVES: Low organisational justice has been shown to be associated with increased risk of various health problems, but the underlying mechanisms remain unclear. We tested whether organisational injustice contributes to chronic inflammation in a population of middle-aged men and women. METHODS: This prospective cohort study uses data from 3205 men and 1204 women aged 35-55 years at entry into the Whitehall II study (phase 1, 1985-1988). Organisational justice perceptions were assessed at phase 1 and phase 2 (1989-1990) and circulating inflammatory markers C-reactive protein (CRP) and interleukin (IL)-6 at phase 3 (1991-1993) and phase 7 (2003-2004). RESULTS: In men, low organisational justice was associated with increased CRP levels at both follow-ups (phase 3 and 7) and increased IL-6 at the second follow-up (phase 7). The long term (phase 7) associations were largely independent of covariates, such as age, employment grade, body mass index and depressive symptoms. In women, no relationship was found between organisational justice and CRP or IL-6. CONCLUSIONS: This study suggests that organisational injustice is associated with increased long-term levels of inflammatory markers among men.
OBJECTIVES: Low organisational justice has been shown to be associated with increased risk of various health problems, but the underlying mechanisms remain unclear. We tested whether organisational injustice contributes to chronic inflammation in a population of middle-aged men and women. METHODS: This prospective cohort study uses data from 3205 men and 1204 women aged 35-55 years at entry into the Whitehall II study (phase 1, 1985-1988). Organisational justice perceptions were assessed at phase 1 and phase 2 (1989-1990) and circulating inflammatory markers C-reactive protein (CRP) and interleukin (IL)-6 at phase 3 (1991-1993) and phase 7 (2003-2004). RESULTS: In men, low organisational justice was associated with increased CRP levels at both follow-ups (phase 3 and 7) and increased IL-6 at the second follow-up (phase 7). The long term (phase 7) associations were largely independent of covariates, such as age, employment grade, body mass index and depressive symptoms. In women, no relationship was found between organisational justice and CRP or IL-6. CONCLUSIONS: This study suggests that organisational injustice is associated with increased long-term levels of inflammatory markers among men.
Authors: Raphael M Herr; Jian Li; Jos A Bosch; Burkhard Schmidt; David M DeJoy; Joachim E Fischer; Adrian Loerbroks Journal: Int Arch Occup Environ Health Date: 2012-12-25 Impact factor: 3.015
Authors: Marko Elovainio; Archana Singh-Manoux; Jane E Ferrie; Martin Shipley; David Gimeno; Roberto De Vogli; Jussi Vahtera; Marianna Virtanen; Markus Jokela; Michael G Marmot; Mika Kivimäki Journal: J Epidemiol Community Health Date: 2010-11-17 Impact factor: 3.710
Authors: Helen C S Meier; Mary N Haan; Carlos F Mendes de Leon; Amanda M Simanek; Jennifer B Dowd; Allison E Aiello Journal: Soc Sci Med Date: 2016-07-05 Impact factor: 4.634
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