| Literature DB >> 19773256 |
Sean H Lim1, Stephen A Beers, Ruth R French, Peter W M Johnson, Martin J Glennie, Mark S Cragg.
Abstract
Antibodies to CD20 have confirmed the hypothesis that monoclonal reagents can be given in vivo to alleviate human diseases. The targeting of CD20 on normal, malignant and auto-immune B-lymphocytes by rituximab has demonstrated substantial benefits for patients with a variety of B-cell lymphomas, as well as some with autoimmune disorders. There has been a notable increase in the survival rates from B-cell lymphoma in the decade since anti-CD20 therapy was introduced.Entities:
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Year: 2009 PMID: 19773256 PMCID: PMC2805725 DOI: 10.3324/haematol.2008.001628
Source DB: PubMed Journal: Haematologica ISSN: 0390-6078 Impact factor: 9.941