Literature DB >> 19772894

PPARs and adipocyte function.

Constantinos Christodoulides1, Antonio Vidal-Puig.   

Abstract

For long viewed as passive lipid storage depots, adipocytes are now recognised as key players in the pathogenesis of insulin resistance and metabolic disease. In parallel, the last two decades of research have seen the emergence of transcription factors of the peroxisome proliferator-activated receptor (PPAR) family as central regulators of lipid and glucose homeostasis and molecular targets for drugs to treat hyper-lipidaemia and type 2 diabetes mellitus. In this review we discuss the characteristics of PPARs and the role of the different isotypes in adipocyte biology. (c) 2009 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19772894     DOI： 10.1016/j.mce.2009.09.014

Source DB:  PubMed          Journal:  Mol Cell Endocrinol        ISSN： 0303-7207            Impact factor:   4.102


  36 in total

1.  Chrysanthemum indicum L. ethanol extract reduces high-fat diet-induced obesity in mice.

Authors:  Ji-Yun Cha; Sarmila Nepali; Hoon-Yeon Lee; Sung-Woo Hwang; Sang-Yong Choi; Jeong-Mo Yeon; Bong-Joon Song; Dae-Ki Kim; Young-Mi Lee
Journal:  Exp Ther Med       Date:  2018-04-10       Impact factor: 2.447

2.  Prepartum fatty acid supplementation in sheep. II. Supplementation of eicosapentaenoic acid and docosahexaenoic acid during late gestation alters the fatty acid profile of plasma, colostrum, milk and adipose tissue, and increases lipogenic gene expression of adipose tissue.

Authors:  Danielle Nicole Coleman; Kevin D Murphy; Alejandro E Relling
Journal:  J Anim Sci       Date:  2018-04-03       Impact factor: 3.159

3.  Antiobesity potential of Piperonal: promising modulation of body composition, lipid profiles and obesogenic marker expression in HFD-induced obese rats.

Authors:  Balaji Meriga; Brahmanaidu Parim; Venkata Rao Chunduri; Ramavat Ravindar Naik; Harishankar Nemani; Pothani Suresh; Saravanan Ganapathy; V V Sathibabu Uddandrao
Journal:  Nutr Metab (Lond)       Date:  2017-11-16       Impact factor: 4.169

Review 4.  Epigenetic Transgenerational Inheritance of Obesity Susceptibility.

Authors:  Stephanie E King; Michael K Skinner
Journal:  Trends Endocrinol Metab       Date:  2020-03-24       Impact factor: 12.015

Review 5.  Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease.

Authors:  Salman Azhar
Journal:  Future Cardiol       Date:  2010-09

6.  Methyl 2-cyano-3,11-dioxo-18-olean-1,12-dien-30-oate (CDODA-Me), a derivative of glycyrrhetinic acid, functions as a potent angiogenesis inhibitor.

Authors:  Xiufeng Pang; Li Zhang; Yougen Wu; Lei Lin; Jingjie Li; Weijing Qu; Stephen Safe; Mingyao Liu
Journal:  J Pharmacol Exp Ther       Date:  2010-07-14       Impact factor: 4.030

7.  Hsp90 chaperones PPARγ and regulates differentiation and survival of 3T3-L1 adipocytes.

Authors:  M T Nguyen; P Csermely; C Sőti
Journal:  Cell Death Differ       Date:  2013-10-04       Impact factor: 15.828

8.  Aspartame downregulates 3T3-L1 differentiation.

Authors:  Muthuraman Pandurangan; Jeongeun Park; Eunjung Kim
Journal:  In Vitro Cell Dev Biol Anim       Date:  2014-06-25       Impact factor: 2.416

9.  Transcriptome analysis of differentially expressed genes in rabbits' ovaries by digital gene-expression profiling.

Authors:  Tao Huang; Ya-Dong Wang; Ming-Ming Xue; Xue Feng; Cai-Xia Sun; An-Si Wang; Shu-Yu Xie; Meng Zhang; Gui-Rong Sun; Ming Li
Journal:  Genes Genomics       Date:  2018-03-26       Impact factor: 1.839

Review 10.  Peroxisome proliferator-activated receptors for hypertension.

Authors:  Daisuke Usuda; Tsugiyasu Kanda
Journal:  World J Cardiol       Date:  2014-08-26
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.