Literature DB >> 19772

Use of DRL in differentiating anxiolytic and neuroleptic properties of CNS drugs.

J G Canon, A S Lippa.   

Abstract

Presented in this paper are the effects of chlorpromazine, clozapine, d-amphetamine and diazepam on DRL behavior in rats. D-Amphetamine and diazepam, which showed similar effects on response errors, could be identified on the basis of burst responding and drug interaction. Clozapine, a new antipsychotic agent which does not cause extrapyramidal side effect in man affected DRL behavior in the same way as did chlorpromazine. Thus, DRL schedules are probably not useful in differentiating various neuroleptic agents.

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Year:  1977        PMID： 19772     DOI： 10.1016/0091-3057(77)90122-8

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  9 in total

1.  A comparison of clozapine, chlorpromazine, and thioridazine upon DRL performance in the squirrel monkey.

Authors:  J G Canon
Journal:  Psychopharmacology (Berl)       Date:  1979-06-28       Impact factor: 4.530

2.  Benzodiazepines reduce the tolerance to reward delay in rats.

Authors:  M H Thiébot; C Le Bihan; P Soubrié; P Simon
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

3.  Picrotoxin-diazepam interaction in a behavioural schedule of differential reinforcement of low rates.

Authors:  P Soubrié; M H Thiébot; A Jobert
Journal:  Experientia       Date:  1978-12-15

4.  Alprazolam, caffeine and their interaction: relating DRL performance to pharmacokinetics.

Authors:  C E Lau; J Wang
Journal:  Psychopharmacology (Berl)       Date:  1996-07       Impact factor: 4.530

5.  Impaired acquisition of temporal differentiation performance following lesions of the ascending 5-hydroxytryptaminergic pathways.

Authors:  M A Wogar; C M Bradshaw; E Szabadi
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

6.  Is delay of reward mediated by shock-avoidance behavior a critical target for anti-punishment effects of diazepam in rats?

Authors:  M H Thiébot; P Soubrié; P Simon
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

7.  Comparison between the effects of propranolol and chlordiazepoxide on timing behaviour in the rat.

Authors:  P Salmon; J A Gray
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

8.  The effects of caffeine on timing behaviour in rodents: comparisons with chlordiazepoxide.

Authors:  D J Sanger
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

Review 9.  Impulsive actions and choices in laboratory animals and humans: effects of high vs. low dopamine states produced by systemic treatments given to neurologically intact subjects.

Authors:  Valérie D'Amour-Horvat; Marco Leyton
Journal:  Front Behav Neurosci       Date:  2014-12-23       Impact factor: 3.558
  9 in total

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