| Literature DB >> 19769733 |
Jacques Banchereau1, Eynav Klechevsky, Nathalie Schmitt, Rimpei Morita, Karolina Palucka, Hideki Ueno.
Abstract
Dendritic cells (DCs) orchestrate a repertoire of immune responses that endow resistance to infection and tolerance to self. DC plasticity and subsets are prominent determinants of the quality of elicited immune responses. Different DC subsets display different receptors and surface molecules and express different sets of cytokines/chemokines, all of which lead to distinct immunological outcomes. Recent findings on human DC subsets and their functional specialization have provided insights for the design of novel human vaccines.Entities:
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Year: 2009 PMID: 19769733 PMCID: PMC2759267 DOI: 10.1111/j.1749-6632.2009.04999.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN: 0077-8923 Impact factor: 5.691