Literature DB >> 19768988

Aaptamine alkaloids from the Vietnamese sponge Aaptos sp.

Larisa K Shubina1, Anatoly I Kalinovsky, Sergey N Fedorov, Oleg S Radchenko, Vladimir A Denisenko, Pavel S Dmitrenok, Sergey A Dyshlovoy, Vladimir B Krasokhin, Valentin A Stonik.   

Abstract

A series of aaptamines, including one new alkaloid (1), were isolated from the marine sponge Aaptos sp. collected in Vietnamese waters. The structure of 1 was elucidated using NMR and HRESIMS, as well as by chemical transformation of 1 to the previously known aaptamine and established as 3-N-morpholinyl-9-demethyl(oxy)aaptamine. The isolated compounds showed a potential cancer preventive activity.

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Year:  2009        PMID： 19768988

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN： 1555-9475            Impact factor:   0.986


  7 in total

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Journal:  Mar Drugs       Date:  2014-03-28       Impact factor: 5.118

2.  A novel benzo[f][1,7]naphthyridine produced by Streptomyces albogriseolus from mangrove sediments.

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3.  Antioxidant and UV-radiation absorption activity of aaptamine derivatives - potential application for natural organic sunscreens.

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Journal:  RSC Adv       Date:  2021-06-17       Impact factor: 4.036

4.  New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein.

Authors:  Sergey A Dyshlovoy; Larisa K Shubina; Tatyana N Makarieva; Jessica Hauschild; Nadja Strewinsky; Alla G Guzii; Alexander S Menshov; Roman S Popov; Boris B Grebnev; Tobias Busenbender; Su Jung Oh-Hohenhorst; Tobias Maurer; Derya Tilki; Markus Graefen; Carsten Bokemeyer; Valentin A Stonik; Gunhild von Amsberg
Journal:  Sci Rep       Date:  2022-08-09       Impact factor: 4.996

Review 5.  Marine low molecular weight natural products as potential cancer preventive compounds.

Authors:  Valentin A Stonik; Sergey N Fedorov
Journal:  Mar Drugs       Date:  2014-01-27       Impact factor: 5.118

6.  Aaptamines from the marine sponge Aaptos sp. display anticancer activities in human cancer cell lines and modulate AP-1-, NF-κB-, and p53-dependent transcriptional activity in mouse JB6 Cl41 cells.

Authors:  Sergey A Dyshlovoy; Sergey N Fedorov; Larisa K Shubina; Alexandra S Kuzmich; Carsten Bokemeyer; Gunhild Keller-von Amsberg; Friedemann Honecker
Journal:  Biomed Res Int       Date:  2014-07-23       Impact factor: 3.411

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Journal:  Mar Drugs       Date:  2020-09-21       Impact factor: 5.118
  7 in total

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